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3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 1

Known as: EC 1.3.1.30, SR Type 1, Steroid 5-Alpha-Reductase Type I 
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (259 aa, ~29 kDa) is encoded by the human SRD5A1 gene. This protein is involved in sexual differentiation and… 
National Institutes of Health

Related topics

Related topics

11 relations
Androgen Metabolism ProcessEnzyme GeneIntegral Membrane ProteinsLiver parenchyma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Synthesis and rat prostate 5-Alpha reductase inhibitions of methylated quercetin derivatives page 168-171
Interested in chemical and biological properties of polymethoxyflavones, a series of methylated quercetin derivatives were… 
Review
2015
Review
2015
5-Alpha Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia:A Systematic Review and Meta-Analysis
Introduction: Finasteride and dutasteride are competitive inhibitors of 5-alpha reductase (5AR) enzymes and are commonly used for… 
2014
2014
The Synergy Effect of Acorus gramineus Soland, Peanut (Arachis hypogaea) Sprouts and Cynanchum Wilfordii Extracts on Inhibition of 5-Alpha Reductase Activity
2013
2013
Etiologies of 46,XY disorders of sex development (DSD): a collaborative study in Hong Kong
Disorders of sex development (DSD) are defined as congenital conditions in which development of chromosomal, gonadal or… 
2011
2011
Long-Term Effect of Loxoprofen Sodium on Nocturia in Patients with Benign Prostatic Hyperplasia
Purpose We evaluated the long-term effects of loxoprofen on nocturia in patients with benign prostatic hyperplasia (BPH… 
2009
2009
Evaluation of MENT on primary cell cultures from benign prostatic hyperplasia and prostate carcinoma.
7-alpha-Methyl-19-Nortestosterone (MENT) is a synthetic androgen more potent than testosterone (T) and cannot be reduced at 5… 
2009
2009
[Efficacy and safety of combined treatment of prostatic adenoma with 5-alpha reductase and alpha-adrenoblockers].
Pharmacotherapy of prostatic adenoma is based in present-day practice primarily on two basic groups of medicines--inhibitors of… 
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