SOCS1 wt Allele

Known as: STAT Induced SH3 Protein 1 Gene, CIS1, SSI1 
Human SOCS1 wild-type allele is located in the vicinity of 16p13.13 and is approximately 2 kb in length. This allele, which encodes suppressor of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
051019962018

Papers overview

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Highly Cited
2004
Highly Cited
2004
Using a candidate gene approach, we analyzed the methylation status of the promoter-associated CpG islands of 11 well… (More)
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Highly Cited
2003
Highly Cited
2003
The suppressor of cytokine signaling (SOCS) family of proteins has been implicated in the negative regulation of several cytokine… (More)
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Highly Cited
2002
Highly Cited
2002
SOCS-1 is a negative regulatory molecule of the JAK-STAT signal cascade. Here, we demonstrate that SOCS-1 is a critical… (More)
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Highly Cited
2002
Highly Cited
2002
Plant pathogen resistance is mediated by a large repertoire of resistance (R) genes, which are often clustered in the genome and… (More)
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Highly Cited
2001
Highly Cited
2001
Hepatocellular carcinoma (HCC) is a major cause of cancer death, but the molecular mechanism for its development beyond its… (More)
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Highly Cited
2001
Highly Cited
2001
During infection, the functional status of the innate immune system is tightly regulated. Although signals resulting in… (More)
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Highly Cited
2001
Highly Cited
2001
Fusion of the TEL gene on 12p13 to the JAK2 tyrosine kinase gene on 9p24 has been found in human leukemia. TEL-mediated… (More)
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Highly Cited
2000
Highly Cited
2000
Interferon (IFN)-alpha has proven useful for treating several clinical conditions, including chronic viral hepatitis and chronic… (More)
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Highly Cited
1999
Highly Cited
1999
The Arabidopsis NPR1 gene was previously shown to be required for the salicylic acid (SA)- and benzothiadiazole (BTH)-induced… (More)
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Highly Cited
1998
Highly Cited
1998
Growth, differentiation, and programmed cell death (apoptosis) are mainly controlled by cytokines. The Janus kinase-signal… (More)
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