SOCS1 gene

Known as: Suppressor of Cytokine Signaling 1 Gene, CIS1, SOCS1 
This gene is involved in the attenuation of cytokine signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
051019972017

Papers overview

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2012
2012
Cytokine and cytokine receptor genes, including IL2RA, IL7R and IL12A, are known risk factors for multiple sclerosis (MS… (More)
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2010
2010
PRINCIPLES It has been postulated that the induced suppressor of cytokine signalling (SOCS) protein inhibits the signalling… (More)
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2007
2007
Beta-site APP cleaving enzyme 1 (BACE1) is an essential enzyme for the production of beta amyloid. Since we found that injection… (More)
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2007
2007
Suppressor of cytokine signaling (SOCS) 1 is an essential physiologic regulator of the IFN-gamma signaling that is crucial to… (More)
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2006
2006
We have previously shown that ASK1 undergoes ubiquitination and degradation in resting endothelial cells (EC) and that… (More)
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2004
2004
Calcineurin is a highly conserved regulator of Ca(2+) signaling in eukaryotes. In fission yeast, calcineurin is not essential for… (More)
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Highly Cited
2003
Highly Cited
2003
The suppressor of cytokine signaling (SOCS) family of proteins has been implicated in the negative regulation of several cytokine… (More)
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Highly Cited
2002
Highly Cited
2002
Aberrant methylation of CpG islands and genomic deletion are two predominant mechanisms of gene inactivation in tumorigenesis… (More)
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2002
2002
SOCS proteins take part in a classical negative feedback loop to attenuate cytokine signaling. Although STAT family members… (More)
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Highly Cited
1997
Highly Cited
1997
Upon the corresponding ligand's stimulation, the cytokine receptors activate several signal pathways: JAK-STAT pathway, Ras-MAP… (More)
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