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SOCS1 gene

Known as: Suppressor of Cytokine Signaling 1 Gene, CIS1, SOCS1 
This gene is involved in the attenuation of cytokine signaling.
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
The mitoCPR unclogs mitochondria The import of proteins into mitochondria is essential for cell viability. How cells respond when… Expand
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2017
2017
Membrane intrinsic proteins (MIPs) form transmembrane channels and facilitate transport of myriad substrates across the cell… Expand
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2014
2014
Macrophages activation which releases the pro-inflammatory cytokines is an essential event in the process of inflammation. SOCS1… Expand
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Highly Cited
2013
Highly Cited
2013
MicroRNAs (miRs) seem to mediate renal fibrosis in several renal diseases, with some miRs having profibrotic effects and others… Expand
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2012
2012
Cytokine and cytokine receptor genes, including IL2RA, IL7R and IL12A, are known risk factors for multiple sclerosis (MS… Expand
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Highly Cited
2007
Highly Cited
2007
The CpG island methylator phenotype (CIMP or CIMP-high) with extensive promoter methylation is a distinct phenotype in colorectal… Expand
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Highly Cited
2006
Highly Cited
2006
We have previously shown that ASK1 undergoes ubiquitination and degradation in resting endothelial cells (EC) and that… Expand
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Highly Cited
2002
Highly Cited
2002
Plant pathogen resistance is mediated by a large repertoire of resistance (R) genes, which are often clustered in the genome and… Expand
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Highly Cited
2002
Highly Cited
2002
SOCS proteins take part in a classical negative feedback loop to attenuate cytokine signaling. Although STAT family members… Expand
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Highly Cited
2002
Highly Cited
2002
Aberrant methylation of CpG islands and genomic deletion are two predominant mechanisms of gene inactivation in tumorigenesis… Expand
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