Skip to search formSkip to main contentSkip to account menu

SLC8A1 wt Allele

Known as: CNC, NCX1, Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 1 wt Allele 
Human SLC8A1 wild-type allele is located in the vicinity of 2p22.1 and is approximately 514 kb in length. This allele, which encodes sodium/calcium… 
National Institutes of Health

Related topics

Related topics

7 relations
Cardiac Muscle ContractionHomo sapiensIonophore activityLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Cells expressing unique Na+/Ca2+ exchange (NCX1) splice variants exhibit different susceptibilities to Ca2+ overload.
The Na+/Ca2+ exchanger (NCX) NCX1 exhibits tissue-specific alternative splicing. Such NCX splice variants as NCX1.1 and NCX1.3… 
Review
2002
Review
2002
Functional Regulation of Alternatively Spliced Na+/Ca2+ Exchanger (NCX1) Isoforms
Abstract: Alternative splicing of RNA transcripts is a general characteristic for NCX genes in mammals, mollusks, and arthropods… 
Highly Cited
2001
Highly Cited
2001
A polymorphic GT repeat from the human cardiac Na+Ca2+ exchanger intron 2 activates splicing.
The sequence analysis of the human intron 2 from the Na+/Ca2+ exchanger 1 (NCX1) gene has revealed a GT repeat of variable length… 
Highly Cited
2001
Highly Cited
2001
Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes.
The functional consequences of overexpression of rat heart Na+/Ca2+ exchanger (NCX1) were investigated in adult rat myocytes in… 
2000
2000
Physiological functions of the regulatory domains of the cardiac Na(+)/Ca(2+) exchanger NCX1.
Physiological functions of the intracellular regulatory domains of the Na(+)/Ca(2+) exchanger NCX1 were studied by examining Ca(2… 
Highly Cited
1998
Highly Cited
1998
Isoform-Specific Regulation of the Na+/Ca2+ Exchanger in Rat Astrocytes and Neurons by PKA
The Na+/Ca2+ exchanger is a major transporter of Ca2+ in neurons and glial cells. The Na+/Ca2+ exchanger gene NCX1 expresses… 
1998
1998
Functional comparison of the three isoforms of the Na 1 / Ca 2 1 exchanger ( NCX 1 , NCX 2 , NCX 3 )
Linck, Bettina, Zhiyong Qiu, Zhaoping He, Qiusheng Tong, Donald W. Hilgemann, and Kenneth D. Philipson. Functional comparison of… 
1997
1997
Identification, expression pattern and potential activity of Na/Ca exchanger isoforms in rat pancreatic B-cells.
1997
1997
Transport and Regulation of the Cardiac Na+-Ca2+ Exchanger, NCX1
Cardiac muscle fails to relax upon replacement of extracellular Ca2+ with Ba2+. Among the manifold consequences of this… 
Highly Cited
1992
Highly Cited
1992
Identification and localization of renal Na(+)-Ca2+ exchanger by polymerase chain reaction.
The molecular identity of the renal Na(+)-Ca2+ exchanger was determined by a homology-based polymerase chain reaction (PCR… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)