SLC7A11 gene

Known as: SOLUTE CARRIER FAMILY 7 (CATIONIC AMINO ACID TRANSPORTER, y+ SYSTEM), MEMBER 11, solute carrier family 7 member 11, SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN 
This gene plays a role in amino acid transport.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
020406019842017

Papers overview

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2011
2011
MicroRNAs are widely dysregulated in various cancers and integrated into tumorigenic programs as either oncogenes or tumor… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The cystine-glutamate exchanger is downregulated after chronic cocaine, resulting in reduced extracellular levels of… (More)
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2009
Highly Cited
2009
In amyotrophic lateral sclerosis, down-regulation of the astrocyte-specific glutamate excitatory amino acid transporter 2 is… (More)
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2008
Highly Cited
2008
The glutathione-dependent system is one of the key systems regulating cellular redox balance, and thus cell fate. Cysteine… (More)
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2005
2005
In mammals, >100 genes regulate pigmentation by means of a wide variety of developmental, cellular, and enzymatic mechanisms… (More)
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Highly Cited
2005
Highly Cited
2005
SLC7A11 (xCT), together with SLC3A2 (4F2hc), encodes the heterodimeric amino acid transport system x(c)-, which mediates cystine… (More)
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Highly Cited
2005
Highly Cited
2005
Cystine/glutamate transporter, designated as system x(-)(c), mediates cystine entry in exchange for intracellular glutamate in… (More)
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Highly Cited
2002
Highly Cited
2002
In mammalian cultured cells, the cystine/glutamate exchange transport mediated by system x(c)- is important to maintain… (More)
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2001
2001
PURPOSE The purpose of this investigation was to provide evidence for the expression of the cystine/glutamate transporter (x(c… (More)
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Highly Cited
1999
Highly Cited
1999
Transport system xc- found in plasma membrane of cultured mammalian cells is an exchange agency for anionic amino acids with high… (More)
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