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SLC7A11 wt Allele

Known as: SLC7A11, XCT, Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 wt Allele 
Human SLC7A11 wild-type allele is located within 4q28-q32 and is approximately 78 kb in length. This allele, which encodes cystine/glutamate… 
National Institutes of Health

Papers overview

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2020
2020
Slc7a11 is the key component of system Xc−, an antiporter that imports cystine (CySS) and exports glutamate. It plays an… 
2018
2018
Deoxynivalenol (DON) is a toxin found in cereals as well as in processed products such as pasta, and causes substantial economic… 
2018
2018
An important micronutrient, iron is used by the cell either as an ion or upon assembly into heme or ironsulfur cluster (ISC… 
Review
2016
Review
2016
Primary tumors of the brain account for 2 % of all cancers with malignant gliomas taking the lion’s share at 70 %. Malignant… 
2014
2014
Background: Some drugs of abuse down regulate the expression of cystine/glutamate (xCT) antiporter in the nucleus accumbens (Acb… 
2011
2011
Medulloblastoma, a neuroectodermal tumor arising in the cerebellum, is the most common brain tumor found in children. We recently… 
2010
2010
The xc− cystine/glutamate antiporter has been implicated in GSH-based chemoresistance because it mediates cellular uptake of… 
2010
2010
KSHV (Kaposi's sarcoma-associated herpesvirus), or HHV-8 (human herpesvirus 8), is associated with the pathogenesis of KS, the…