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SLC7A11 wt Allele
Known as:
SLC7A11
, XCT
, Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 wt Allele
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Human SLC7A11 wild-type allele is located within 4q28-q32 and is approximately 78 kb in length. This allele, which encodes cystine/glutamate…
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National Institutes of Health
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Related topics
Related topics
8 relations
4q28-q32
Cystine/Glutamate Transporter Protein
Homo sapiens
Intracellular Transport
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Broader (1)
SLC7A11 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Redox States of Protein Cysteines in Pathways of Protein Turnover and Cytoskeleton Dynamics Are Changed with Aging and Reversed by Slc7a11 Restoration in Mouse Lung Fibroblasts
Yuxuan Zheng
,
M. Merchant
,
+6 authors
W. H. Watson
Oxidative Medicine and Cellular Longevity
2020
Corpus ID: 220043236
Slc7a11 is the key component of system Xc−, an antiporter that imports cystine (CySS) and exports glutamate. It plays an…
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2018
2018
Deoxynivalenol Affects Cell Metabolism and Increases Protein Biosynthesis in Intestinal Porcine Epithelial Cells (IPEC-J2): DON Increases Protein Biosynthesis
Constanze Nossol
,
P. Landgraf
,
+6 authors
H. Rothkötter
Toxins
2018
Corpus ID: 53306092
Deoxynivalenol (DON) is a toxin found in cereals as well as in processed products such as pasta, and causes substantial economic…
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2018
2018
Leveraging the iron-starvation response to promote ferroptosis
Samantha W. Alvarez
,
Richard L. Possemato
OncoTarget
2018
Corpus ID: 36007751
An important micronutrient, iron is used by the cell either as an ion or upon assembly into heme or ironsulfur cluster (ISC…
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Review
2016
Review
2016
Epigenetics in Brain Tumors: HDACs Take Center Stage
I. Eyüpoglu
,
N. Savaskan
Current Neuropharmacology
2016
Corpus ID: 14930875
Primary tumors of the brain account for 2 % of all cancers with malignant gliomas taking the lion’s share at 70 %. Malignant…
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2016
2016
xCT deficiency induces autophagy via endoplasmic reticulum stress activated p38-mitogen-activated protein kinase and mTOR in sut melanocytes.
Xueting Zheng
,
Yang Li
,
+4 authors
Haixuan Qiao
European Journal of Cell Biology
2016
Corpus ID: 25913557
2014
2014
Change of cystine/glutamate antiporter expression in ethanol-dependent rats
A. Peana
,
G. Muggironi
,
F. Bennardini
Frontiers in Neuroscience
2014
Corpus ID: 17177735
Background: Some drugs of abuse down regulate the expression of cystine/glutamate (xCT) antiporter in the nucleus accumbens (Acb…
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2011
2011
Antitumor activity of nifurtimox is enhanced with tetrathiomolybdate in medulloblastoma.
K. Koto
,
P. Lescault
,
+7 authors
G. S. Saulnier Sholler
International Journal of Oncology
2011
Corpus ID: 25825953
Medulloblastoma, a neuroectodermal tumor arising in the cerebellum, is the most common brain tumor found in children. We recently…
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2010
2010
Pharmacogenomic Approach Reveals a Role for the xc− Cystine/Glutamate Antiporter in Growth and Celastrol Resistance of Glioma Cell Lines
A. Pham
,
P. Blower
,
O. Alvarado
,
Ranadheer Ravula
,
P. Gout
,
Ying Huang
Journal of Pharmacology and Experimental…
2010
Corpus ID: 5862826
The xc− cystine/glutamate antiporter has been implicated in GSH-based chemoresistance because it mediates cellular uptake of…
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2010
2010
Overexpression of xCT induces up-regulation of 14-3-3β in Kaposi's sarcoma
Yan Zeng
,
Yan Li
,
Ri-Sheng Chen
,
Xin He
,
Lei Yang
,
Wei Li
Bioscience Reports
2010
Corpus ID: 11071421
KSHV (Kaposi's sarcoma-associated herpesvirus), or HHV-8 (human herpesvirus 8), is associated with the pathogenesis of KS, the…
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2009
2009
Aggravation of ischemia-reperfusion-triggered acute renal failure in xCT-deficient mice.
T. Shibasaki
,
Y. Iuchi
,
+6 authors
J. Fujii
Archives of Biochemistry and Biophysics
2009
Corpus ID: 20359899
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