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SLC28A1 wt Allele
Known as:
CNT1
, HCNT1
, Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 1 wt Allele
Human SLC28A1 wild-type allele is located in the vicinity of 15q25.3 and is approximately 61 kb in length. This allele, which encodes sodium…
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National Institutes of Health
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Related topics
Related topics
6 relations
Homo sapiens
Ligand Binding
Molecular Transport
Nucleotide Metabolism
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Broader (1)
SLC28A1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Hepatobiliary transporter expression in human hepatocellular carcinoma
G. Zollner
,
M. Wagner
,
+5 authors
M. Trauner
Liver international (Print)
2005
Corpus ID: 27362258
Abstract: Background/Aims: Treatment of hepatocellular carcinoma (HCC) is hampered by resistance to chemotherapy, which might be…
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Highly Cited
2004
Highly Cited
2004
Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1.
Cheng Chang
,
P. Swaan
,
L. Ngo
,
P. Lum
,
S. D. Patil
,
J. Unadkat
Molecular Pharmacology
2004
Corpus ID: 17156962
Concentrative nucleoside transporters (CNTs) and equilibrative nucleoside transporters (ENTs) are important in physiological and…
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Highly Cited
2004
Highly Cited
2004
Expression of the nucleoside‐derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors
X. Farré
,
E. Guillén-Gómez
,
+6 authors
M. Pastor-Anglada
International Journal of Cancer
2004
Corpus ID: 33828164
Deoxynucleoside analogs are used in the treatment of a variety of solid tumors. Their transport across the plasma membrane may…
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Highly Cited
2003
Highly Cited
2003
Nucleoside transporter profiles in human pancreatic cancer cells: role of hCNT1 in 2',2'-difluorodeoxycytidine- induced cytotoxicity.
J. Garcia-Manteiga
,
M. Molina-Arcas
,
F. Casado
,
A. Mazo
,
M. Pastor-Anglada
Clinical Cancer Research
2003
Corpus ID: 17597320
PURPOSE Concentrative nucleoside transporter (CNT) 1, CNT3, equilibrative nucleoside transporter (ENT) 1, and, to a lesser extent…
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Highly Cited
2003
Highly Cited
2003
Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia.
M. Molina-Arcas
,
B. Bellosillo
,
+4 authors
M. Pastor-Anglada
Blood
2003
Corpus ID: 15515068
Nucleoside derivatives are currently used in the treatment of hematologic malignancies. Although intracellular events involved in…
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Highly Cited
2003
Highly Cited
2003
The Exocyst Affects Protein Synthesis by Acting on the Translocation Machinery of the Endoplasmic Reticulum*
J. Lipschutz
,
V. Lingappa
,
K. Mostov
Journal of Biological Chemistry
2003
Corpus ID: 12049445
We previously showed that the exocyst complex specifically affected the synthesis and delivery of secretory and basolateral…
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Highly Cited
2001
Highly Cited
2001
Differential expression of human nucleoside transporters in normal and tumor tissue.
Micha Pennycooke
,
Naz Chaudary
,
Irina Shuralyova
,
Ying Zhang
,
I. Coe
Biochemical and Biophysical Research…
2001
Corpus ID: 858189
Responses to nucleoside analog drugs used in the treatment of cancers and viral infections can vary considerably between…
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Highly Cited
2000
Highly Cited
2000
Selective loss of nucleoside carrier expression in rat hepatocarcinomas
Y. Dragan
,
R. Valdés
,
+4 authors
M. Pastor-Anglada
Hepatology
2000
Corpus ID: 20597319
Evidence that hepatoma cell lines show differential expression of concentrative nucleoside transporters (CNT1 and CNT2) prompted…
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Highly Cited
1999
Highly Cited
1999
Identification of Amino Acid Residues Responsible for the Pyrimidine and Purine Nucleoside Specificities of Human Concentrative Na+ Nucleoside Cotransporters hCNT1 and hCNT2*
Shauna Loewen
,
A. Ng
,
S. Yao
,
C. Cass
,
S. Baldwin
,
J. Young
Journal of Biological Chemistry
1999
Corpus ID: 260589169
hCNT1 and hCNT2 mediate concentrative (Na+-linked) cellular uptake of nucleosides and nucleoside drugs by human cells and tissues…
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Highly Cited
1997
Highly Cited
1997
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).
M. Ritzel
,
S. Yao
,
M.-Y. Huang
,
J. Elliott
,
C. Cass
,
J. Young
American Journal of Physiology
1997
Corpus ID: 25034233
We report identification of a new human nucleoside transporter protein by molecular cloning and functional expression of its cDNA…
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