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SLC12A5 gene

Known as: SLC12A5, KCC2, solute carrier family 12 member 5 
National Institutes of Health

Related topics

Related topics

1 relation
SLC12A6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
KCC2 Regulates Neuronal Excitability and Hippocampal Activity via Interaction with Task-3 Channels.
2016
2016
Compromising KCC2 transporter activity enhances the development of continuous seizure activity
Highly Cited
2015
Highly Cited
2015
BDNF is required for seizure-induced but not developmental up-regulation of KCC2 in the neonatal hippocampus
2013
2013
An unexpected role of neuroligin-2 in regulating KCC2 and GABA functional switch
BackgroundGABAA receptors are ligand-gated Cl- channels, and the intracellular Cl- concentration governs whether GABA function is… 
2011
2011
Components of neuronal chloride transport in rat and human neocortex
Non‐technical summary  The inhibitory neurotransmitter GABA activates two distinct receptors of which the GABAA receptor is… 
2008
2008
The RCC1 Domain of Protein Associated with Myc (PAM) Interacts with and Regulates KCC2
GABAergic and glycinergic function is dependent on neuronal intracellular chloride. The neuron-specific electroneutral potassium… 
2008
2008
Molecular, pharmacological and functional properties of GABAA receptors in anterior pituitary cells
Anterior pituitary cells express γ‐aminobutyric acid (GABA)‐A receptor‐channels, but their structure, distribution within the… 
Highly Cited
2003
Highly Cited
2003
Role of sex hormones in the sexually dimorphic expression of KCC2 in rat substantia nigra
2003
2003
Heterogeneous expression of the potassium-chloride cotransporter KCC2 in gonadotropin-releasing hormone neurons of the adult mouse.
In mature central neurons, chloride extrusion mediated by the K-Cl cotransporter KCC2 appears to be largely responsible for the… 
Highly Cited
2000
Highly Cited
2000
Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue.
K-Cl cotransporters (KCC) play fundamental roles in ionic and osmotic homeostasis. To date, four mammalian KCC genes have been… 
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