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SH3BP2 wt Allele

Known as: 3BP-2, CRPM, SH3-Domain Binding Protein 2 wt Allele 
Human SH3BP2 wild-type allele is located 4p16.3 and is approximately 48 kb in length. This allele, which encodes SH3 domain-binding protein 2, is… 
National Institutes of Health

Related topics

Related topics

5 relations
4p16.3CherubismSignal Transductionprotein protein interaction

Broader (1)

SH3BP2 gene

Papers overview

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Highly Cited
2014
Highly Cited
2014
Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover.
Highly Cited
2011
Highly Cited
2011
3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions.
A fine balance between bone resorption by osteoclasts and bone formation by osteoblasts maintains bone homeostasis. In patients… 
2011
2011
A Concerted HIF-1α/MT1-MMP Signalling Axis Regulates the Expression of the 3BP2 Adaptor Protein in Hypoxic Mesenchymal Stromal Cells
Increased plasticity, migratory and immunosuppressive abilities characterize mesenchymal stromal cells (MSC) which enable them to… 
Review
2006
Review
2006
Noonan-like/multiple giant cell lesion syndrome: report of a case and review of the literature.
Highly Cited
2005
Highly Cited
2005
The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor.
Engagement of the B-cell antigen receptor (BCR) activates kinases of the Src and Syk families and signaling complexes assembled… 
2005
2005
The Adaptor Protein 3BP2 Binds Human CD244 and Links this Receptor to Vav Signaling, ERK Activation, and NK Cell Killing1
Adaptor proteins, molecules that mediate intermolecular interactions, are crucial for cellular activation. The adaptor 3BP2 has… 
Highly Cited
2003
Highly Cited
2003
The Chaperone Protein 14-3-3 Interacts with 3BP2/SH3BP2 and Regulates Its Adapter Function*
Lymphocyte stimulation by immunoreceptors is achieved through the activation of multiple signaling pathways leading to cytokine… 
Highly Cited
2002
Highly Cited
2002
Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expressing transgenic cell line S1 of Catharanthus roseus
The transgenic S1 cell line of Catharanthus roseus (L.) G. Don has been used to study possible rate limiting steps in the… 
Highly Cited
2001
Highly Cited
2001
Regulation of NK Cell-Mediated Cytotoxicity by the Adaptor Protein 3BP21
Stimulation of lymphocytes through multichain immune recognition receptors activates multiple signaling pathways. Adaptor… 
1999
1999
Pathogenicity, Electrophoretic Characterisation and In planta Detection of the Cocoyam Root Rot Disease Pathogen, Pythium myriotylum
Cocoyam (Xanthosoma sagittifolium), an important staple food crop for many people in the tropics and subtropics, suffers great… 
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