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SH3BP2 gene

Known as: SH3-Domain Binding Protein 2 Gene, RES4-23, SH3-domain binding protein 2 
This gene plays a role in signal transduction.
National Institutes of Health

Related topics

Related topics

4 relations
CherubismSignal Transductionprotein protein interaction

Narrower (1)

SH3BP2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Common Skeletal Deformities
2012
2012
Cloning and characterization of the human SH3BP2 promoter.
2011
2011
Decreased SH3BP2 inhibits osteoclast differentiation and function
Germline mutations in SH3BP2 gene have been identified in patients with cherubism, a skeletal disorder characterized by excessive… 
2010
2010
Effect of SH3BP2 gene mutation on the expression of NFATc1 and SH3BP2 proteins in cherubism patients
Objective To investigate the change of signal transduction pathway after the point mutation of SH3BP2 gene.Methods… 
Review
2009
Review
2009
SH3BP2 is a Critical Regulator of Macrophage and Osteoclast Response to M-CSF and RANKL Stimulation
The protein Src homology 3 domain-binding protein 2 (SH3BP2) is a regulator of tumor necrosis factor (TNF)-alpha generation in… 
2008
2008
Mutations in SH3BP2, the cherubism gene, were not detected in central or peripheral giant cell tumours of the jaw.
2008
2008
SH3BP2 is a Critical Regulator of Macrophage and Osteoclast Response to M-CSF and RANKL Stimulation
The protein Src homology 3 domain-binding protein 2 (SH3BP2) is a regulator of tumor necrosis factor (TNF)-alpha generation in… 
2008
2008
Reference No . : 148835 REVISED Adaptor Protein 3 BP 2 and Cherubism
The adaptor protein 3BP2 (c-Abl Src homology 3 domain-binding protein-2, also referred to SH3BP2) is known to play a regulatory… 
2007
2007
SH3BP2 Is Rarely Mutated in Exon 9 in Giant Cell Lesions Outside Cherubism
Giant cell tumor of bone and giant cell reparative granuloma are benign lesions with prominent giant (multinucleated) cells, and… 
Review
2006
Review
2006
[The adaptor protein 3BP2 in leukocyte signaling].
  • M. Deckert
  • Medecine sciences : M/S
  • 2006
  • Corpus ID: 8199630
Adaptor proteins that do not contain intrinsic enzymatic activity play a critical role in cell biology by regulating the assembly… 
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