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The cell fate decision leading to gametogenesis requires the convergence of multiple signals on the promoter of a master… Expand Somatic mutations in spliceosome proteins lead to dysregulated RNA splicing and are observed in a variety of cancers. These… Expand Congenital heart disease (CHD) affects up to 1% of live births. Although a genetic etiology is indicated by an increased… Expand Endophytes are related with health and growth of plants. In this study, the endophytic bacterial strain RSE1 was isolated from… Expand Purpose: Deregulation or mutation of the EZH2 gene causes various tumors, including clear cell renal cell carcinoma (ccRCC… Expand Background and Purpose— Macrophage-inducible C-type lectin (Mincle, CLEC4E) receptor is reported involved in neuroinflammation in… Expand The 5'-ends of all Kinetoplastid mRNAs consist of a short sequence added by trans splicing. In contrast to cis splicing in… Expand Pladienolide is a naturally occurring antitumor macrolide that was discovered by using a cell-based reporter gene expression… Expand BackgroundCullin-RING ubiquitin E3 ligases (CRLs) are regulated by modification of an ubiquitin-like protein, Nedd8 (also known… Expand ABSTRACT The mSin3A corepressor complex contains 7 to 10 tightly associated polypeptides and is utilized by many transcriptional… Expand