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SETDB1 gene

Known as: TDRD21, KMT1E, SET domain bifurcated 1 
This gene is involved in chromatin remodeling and the regulation of transcription.
National Institutes of Health

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Gene ExpressionMethylationProtein methylationSETDB1 protein, human

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SETDB1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
SETDB1 plays an essential role in maintenance of gonocyte survival in pigs.
Histone methyltransferase SETDB1 suppresses gene expression and modulates heterochromatin formation through H3K9me2/3. Previous… 
2016
2016
ΔNp63α modulates histone methyl transferase SETDB1 to transcriptionally repress target genes in cancers
ΔNp63α is primarily expressed in the epithelial tissue, including the mammary gland and epidermis, where it is indispensable to… 
2016
2016
The methyltransferase Setdb 1 is essential for meiosis and mitosis in mouse oocytes and early embryos
Oocytes develop the competence for meiosis and early embryogenesis during their growth. Setdb1 is a histone H3 lysine 9 (H3K9… 
2016
2016
Dysregulation of the epigenetic regulator SETDB1 in liver carcinogenesis-more than one way to skin a cat.
Hepatocellular carcinoma (HCC) is one of the most prevalent human cancers worldwide. Its development is considered a step-wise… 
2015
2015
Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst.
2014
2014
Molecular and Cellular Pathobiology H 3 K 9 Histone Methyltransferase , KMT 1 E / SETDB 1 , Cooperates with the SMAD 2 / 3 Pathway to Suppress Lung Cancer Metastasis
Aberrant histone methylation is a frequent event during tumor development and progression. KMT1E (also known as SETDB1) is a… 
2014
2014
Repair of ruptured abdominal aortic aneurysms with bifurcated endografts: a single-center study
OBJECTIVE: The aim of this study was to describe our early experience in the treatment of ruptured abdominal aortic aneurysms… 
2011
2011
Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice
2007
2007
Regulation of E 2 F 1 Function by the Nuclear
KAP1 is a nuclear corepressor with conserved domains for RING finger, B boxes, leucine zipper helical coiled-coil region, plant… 
Review
2007
Review
2007
Az arteria pulmonalis billentyûjének agenesiája – tíz, praenatálisan diagnosztizált eset elemzése és irodalmi áttekintés = Congenital Absent Pulmonary Valve – analysis of ten prenatally diagnosed…
Celkitűzes: Tiz, praenatalisan diagnosztizalt pulmonalis billentyűagenesia eseteben a tarsulo cardialis, extracardialis es… 
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