Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst.

@article{Golding2015HistonelysineNS,
  title={Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst.},
  author={Michael C Golding and Matthew Snyder and G. LaVerne Williamson and Kylee J. Veazey and Michael Peoples and Jane H. Pryor and Mark E Westhusin and Charles R. Long},
  journal={Theriogenology},
  year={2015},
  volume={84 8},
  pages={1411-22}
}
Transcripts derived from select clades of transposable elements are among the first to appear in early mouse and human embryos, indicating transposable elements and the mechanisms that regulate their activity are fundamental to the establishment of the founding mammalian lineages. However, the mechanisms by which these parasitic sequences are involved in… CONTINUE READING