SCH 50911

Different effects of moderate to high doses of gamma-hydroxybutyric acid, including sedation/hypnosis, have been found to be… (More)

The present study investigated the effect of the GABA(B) receptor antagonist, SCH 50911 [(2S)(+)-5,5-dimethyl-2-morpholineacetic… (More)

The striatum is a crucial site of action for the motor effects of cannabinoids (CBs). However, the electrophysiological… (More)

In many areas of the nervous system, excitatory and inhibitory synapses are reconfigured during early development. We have… (More)

The present study was aimed at identifying the receptor systems involved in the mediation of the sedative/hypnotic effect of… (More)

The gamma-aminobutyric acid type A (GABAA) receptor agonist muscimol is widely used as a tool for reducing neuronal activities… (More)

Previous studies have shown that systemic as well as local administration of the GABAB-receptor agonist baclofen is associated… (More)

Kainate (KA) receptor activation depresses stimulus-evoked gamma-aminobutyric acid (GABA-mediated) synaptic transmission onto CA1… (More)

Experiments were conducted to characterize the pharmacology of SCH 50911 ((+)-5,5-dimethyl-2-morpholineacetic acid hydrochloride… (More)

Recent studies have shown that gamma-aminobutyric acidB (GABAB) receptor antagonists suppress absence seizures in animal models… (More)