Drug Synergism and Dose-Effect Data Analysis
- R. Tallarida
- Medicine
- 21 July 2000
Combinations of Chemicals Dose-Response Analysis Linear Regression: A Further Discussion Calculations for Combination Drug Analysis. The Composite Additive Curve Quantal Dose-Response Data: Probit…
Drug synergism: its detection and applications.
- R. Tallarida
- BiologyJournal of Pharmacology and Experimental…
- 1 September 2001
The relative potency of the agents allows a calculation using dose pairs to determine the equivalent of either agent and the effect by using the equivalent in the dose-response relation of the reference compound.
An Overview of Drug Combination Analysis with Isobolograms
- R. Tallarida
- BiologyJournal of Pharmacology and Experimental…
- 1 October 2006
Determination of the additive isobole is a necessary procedure for assessing both synergistic and antagonistic interactions of the combination and the mathematical formulas needed to distinguish these cases are provided.
The interaction index: a measure of drug synergism
- R. Tallarida
- BiologyPain
- 1 July 2002
Statistical analysis of drug-drug and site-site interactions with isobolograms.
- R. Tallarida, F. Porreca, A. Cowan
- BiologyLife Science
- 1989
Statistical analysis of drug combinations for synergism
- R. Tallarida
- PhysicsPain
- 1 April 1992
Interactions between drugs and occupied receptors.
- R. Tallarida
- BiologyPharmacology and Therapeutics
- 2007
pA2 and receptor differentiation: a statistical analysis of competitive antagonism.
- R. Tallarida, A. Cowan, M. Adler
- BiologyLife Science
- 20 August 1979
Efficient designs for studying synergistic drug combinations.
- R. Tallarida, D. Stone, R. Raffa
- BiologyLife Science
- 21 November 1997
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