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Latanoprost exerts neuroprotective activity in vitro and in vivo.
Prostaglandins may influence cyclo-oxygenase (COX-2) and nitric oxide (NO) synthase activity, thus interfering with ischemia-induced neurotoxic processes. The prostaglandin synthetic derivative,Expand
The morpholino-acetic acid analogue Sch 50911 is a selective GABA(B) receptor antagonist in rat neocortical slices.
The pharmacological properties of (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid (Sch 50911) were evaluated on GABA(B) receptors in rat neocortical slices. The GABA(B) receptor agonist, baclofen,Expand
Evidence for presynaptic cholinergic receptors in sympathetic nerves in human dental pulp.
The purpose of this study was to determine whether presynaptic cholinergic receptors are present in sympathetic nerves in human dental pulp. Pulp was incubated with [3H]noradrenaline (0.6 mumol/l)Expand
Modulation by presynaptic β-adrenoceptors of noradrenaline release from sympathetic nerves in human dental pulp
Abstract This study was undertaken to test for the presence of presynaptic β -adrenoceptors on sympathetic nerves in human dental pulp and, if present, to investigate the subtype. Pulp was excisedExpand
Cocaine-sensitive O-methylation of noradrenaline in dental pulp of the rabbit: Comparison with the rabbit ear artery
SummaryIncisor pulp from the rabbit metabolises exogenous noradrenaline in concentrations between 0.12 and 1.2 μmol/l mainly to NMN.Effects of chronic sympathetic denervation indicated that inExpand
Biochemical changes induced by pyrphenoxone in the lens of rabbits and rats.
The xanthomatine analogue, pyrphenoxone, which is known to diminish the incidence of cataract in animals and in man, was applied in two different in vivo models of cataract induced in rabbits byExpand
3-Chloro,4-methoxyfendiline is a potent GABA(B) receptor potentiator in rat neocortical slices.
Using grease-gap recording from rat neocortical slices, the GABA(B) receptor agonist baclofen elicited reversible and concentration-dependent hyperpolarizing responses (EC50=18+/-2.3 microM). TheExpand
Pharmacological actions of thymol and an analogue at GABAB autoreceptors
GABAB autoreceptors inhibit release of GABA from GABAergic nerve terminals. Agonists of these receptors (e.g. baclofen) inhibit, whereas antagonists (e.g. (+)‐(S)‐5,5‐dimethylmorpholinyl‐2‐aceticExpand
Modulation by presynaptic beta-adrenoceptors of noradrenaline release from sympathetic nerves in human dental pulp.
This study was undertaken to test for the presence of presynaptic beta-adrenoceptors on sympathetic nerves in human dental pulp and, if present, to investigate the subtype. Pulp was excised fromExpand
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