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SC-9420

Known as: SC 9420, SC9420 
National Institutes of Health

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1 relation

Broader (1)

Spironolactone

Papers overview

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2004
2004
The effect of metopirone and aldactone on the interrenal tissue of intact and pars distalis-ectomized common frogs Rana temporaria
SummaryThe effects of metopirone (SU-4885) and aldactone (SC-9420) on the histology and histochemistry of the interrenal tissue… 
2004
2004
Synthesis of aldosterone antagonists
ConclusionsTwo antagonists of aldosterone were synthesized based on ethynyl androstenediol: the γ-lactone of 3-(3-keto-17… 
2000
2000
A Single Amino Acid Mutation of Ala-773 in the Mineralocorticoid Receptor Confers Agonist Properties to 11 b -Substituted Spirolactones
Sequence analysis revealed a strong homology between the ligand-binding domain (LBD) of the human mineralocorticoid receptor (hMR… 
1992
1992
Differences between aldosterone and its antagonists in binding kinetics and ligand-induced hsp90 release from mineralocorticosteroid receptor
1991
1991
Autoradiographic evidence of nuclear binding of spironolactone in rabbit cortical collecting tubule.
Previous biochemical studies indicated that the spirolactone-mineralocorticoid receptor complexes are unable to translocate into… 
1972
1972
The effect of a new anti-aldosterone agent SC19886 on aldosterone-stimulated transepithelial sodium transport.
1966
1966
Blocking byspironolactone (SC9420) oftheaction ofaldosterone upontheintestinal transport of potassium, sodium, andwater
1964
1964
[5 CASES OF MYASTHENIA TREATED WITH SPIRONOLACTONE (SC9420 LEPETIT)].
1962
1962
Hypotensive effect of SC-9420 on 3 cases of primary aldosteronism.
Primary aldosteronism is the disease with resultant various metabolic disorders by increased aldosterone secretion primarily… 
1960
1960
[On the behavior of diuresis and serum and urinary electrolytes during treatment with spirolactone (Sc-9420) in menopausal women].
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