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SB 415286
Known as:
SB-415286
, SB415286
National Institutes of Health
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Highly Cited
2008
Highly Cited
2008
Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal.
B. Sen
,
Zhihui Xie
,
N. Case
,
Meiyun Ma
,
C. Rubin
,
J. Rubin
Endocrinology
2008
Corpus ID: 207058618
The ability of exercise to decrease fat mass and increase bone mass may occur through mechanical biasing of mesenchymal stem…
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Highly Cited
2008
Highly Cited
2008
Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation
Yong-Hak Seo
,
Hyun-Jung Jung
,
+5 authors
G. Yoon
Aging cell
2008
Corpus ID: 205633827
Glycogen biogenesis and its response to physiological stimuli have often been implicated in age‐related diseases. However, their…
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Highly Cited
2008
Highly Cited
2008
Lithium Treatment Decreases Activities of Tau Kinases in a Murine Model of Senescence
M. Tajes
,
J. Gutiérrez-Cuesta
,
+6 authors
M. Pallàs
Journal of neuropathology and experimental…
2008
Corpus ID: 18601971
Lithium modulates glycogen synthase kinase 3β (GSK-3β), a kinase involved in Alzheimer disease-related tau pathology. To…
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Highly Cited
2005
Highly Cited
2005
GSK-3β inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat*
L. Dugo
,
M. Collin
,
+7 authors
C. Thiemermann
Critical care medicine
2005
Corpus ID: 22128914
Objective:Serine-threonine protein kinase glycogen synthase kinase (GSK)-3 is involved in regulation of many cell functions, but…
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Highly Cited
2005
Highly Cited
2005
Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
Jinjiang Dong
,
Junying Peng
,
+5 authors
F. Meric-Bernstam
Cancer research
2005
Corpus ID: 20209286
The mammalian target of rapamycin is a serine-threonine kinase that regulates cell cycle progression. Rapamycin and its analogues…
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Highly Cited
2004
Highly Cited
2004
Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth
M. Mazor
,
Y. Kawano
,
H. Zhu
,
J. Waxman
,
R. Kypta
Oncogene
2004
Corpus ID: 22398804
The transcriptional activity of the androgen receptor (AR) is regulated by interaction with various coregulators, one of which is…
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Highly Cited
2002
Highly Cited
2002
An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling
B. Eickholt
,
F. Walsh
,
P. Doherty
The Journal of cell biology
2002
Corpus ID: 7775338
Glycogen synthase kinase (GSK)-3 is a serine/threonine kinase that has been implicated in several aspects in embryonic…
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Highly Cited
2001
Highly Cited
2001
Inhibition of GSK-3 Selectively Reduces Glucose-6-Phosphatase and Phosphoenolpyruvate Carboxykinase Gene Expression
P. Lochhead
,
M. Coghlan
,
S. Rice
,
C. Sutherland
2001
Corpus ID: 42171499
A major action of insulin is to regulate the transcription rate of specific genes. The expression of these genes is dramatically…
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Highly Cited
2001
Highly Cited
2001
GSK‐3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β‐catenin stabilisation without elevation of glycogen synthase activity
A. Culbert
,
Murray J. Brown
,
+4 authors
A. Reith
FEBS letters
2001
Corpus ID: 43051543
Highly Cited
2000
Highly Cited
2000
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.
M. Coghlan
,
A. Culbert
,
+15 authors
J. Holder
Chemistry & biology
2000
Corpus ID: 23038980
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