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SB 415286

Known as: SB-415286, SB415286 
National Institutes of Health

Papers overview

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2014
2014
Inactivation of glycogen synthase kinase-3β up-regulates β-catenin and promotes chondrogenesis
This study aimed to investigate whether inhibition of glycogen synthase kinase-3β (GSK-3β) could promote chondrocytes… 
2013
2013
Glucose dependence of glycogen synthase activity regulation by GSK3 and MEK/ERK inhibitors and angiotensin-(1-7) action on these pathways in cultured human myotubes.
2011
2011
Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation.
WNT signaling has been shown to influence the development of the heart. Although recent data suggested that canonical WNTs… 
2010
2010
Molecular imaging of glycogen synthase kinase-3beta and casein kinase-1alpha kinases.
2009
2009
Glycogen synthase kinase-3 inhibitors augment TRAIL-induced apoptotic death in human hepatoma cells.
2009
2009
Chronic lithium treatment up-regulates cell surface NaV1.7 sodium channels via inhibition of glycogen synthase kinase-3 in adrenal chromaffin cells: Enhancement of Na+ influx, Ca2+ influx and…
2008
2008
Up-regulation of protein l-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and β-catenin stabilization
2008
2008
25-Hydroxycholesterol induces mitochondria-dependent apoptosis via activation of glycogen synthase kinase-3β in PC12 cells
25-Hydroxycholesterol (25-OH-chol) induces apoptosis in many cell types. The present study investigated the possible involvement… 
2007
2007
Inhibiting glycogen synthase kinase 3beta in sepsis.
The serine-threonine protein kinase glycogen synthase kinase (GSK)-3 is involved in the regulation of many cell functions, but… 
2005
2005
Lithium Chloride Increases the Production of Amyloid-β Peptide Independently from Its Inhibition of Glycogen Synthase Kinase 3*
Glycogen synthase kinase 3 (GSK3) is able to phosphorylate tau at many sites that are found to be phosphorylated in paired… 
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