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SB 209670

Known as: SB-209670 
National Institutes of Health

Papers overview

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2014
2014
Dual blockade of endothelin action exacerbates up-regulated VEGF angiogenic signaling in the heart of lipopolysaccharide-induced endotoxemic rat model.
2000
2000
Identification of a novel kidney-specific gene downregulated in acute ischemic renal failure.
To gain further insights into the molecular mechanisms involved in acute renal failure, we have isolated a new gene from rat and… 
1999
1999
Developmental toxicity and toxicokinetics of two endothelin receptor antagonists in rats and rabbits.
Embryo-fetal development studies with toxicokinetic evaluations were conducted in rats and rabbits after oral or intravenous… 
1999
1999
Endothelin mediates renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats.
Profound vasodilation of the kidneys and other nonreproductive organs transpires during early pregnancy. Because nitric oxide (NO… 
1999
1999
Trigeminal nerve ganglion stimulation‐induced neurovascular reflexes in the anaesthetized cat: Role of endothelinB receptors in carotid vasodilatation
The effects of intravenous administration of endothelin (ET) receptor antagonists SB‐209670 (0.001–10.0 mg kg−1), SB‐217242, SB… 
1998
1998
Endothelin ET(B) receptors show different binding profiles in intact cells and cell membrane preparations.
1998
1998
Cardiovascular actions of ET-B activation in vivo and modulation by receptor antagonism.
The endothelin (ET)-B receptor subtype is expressed on vascular endothelial and smooth muscle cells and participates in… 
1996
1996
Effects of dexamethasone and SB 209670 on the regional haemodynamic responses to lipopolysaccharide in conscious rats
1 . Male (350–450 g) Long Evans rats were chronically instrumented to permit regional haemodynamics to be monitored in the… 
1995
1995
Endothelin Receptor Subtypes in the Pathogenesis of Angioplasty‐Induced Neointima Formation in the Rat: A Comparison of Selective ETA Receptor Antagonism and Dual ETA/ETB Receptor Antagonism Using BQ…
Summary: The present study compared the vasculo-protective efficacy of acute and chronic endothelin (ET) ETA or dual ETA/B… 
1995
1995
Binding of the nonpeptide antagonist, SB 209670, to endothelin receptors on cultured neurons
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