S1PR1 gene

Known as: Sphingosine-1-Phosphate Receptor 1 Gene, D1S3362, edg-1 
This gene plays a role in lipid binding.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Activation of the ER stress response is associated with malignant progression of B cell chronic lymphocytic leukemia (CLL). We… (More)
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Highly Cited
2013
Highly Cited
2013
Cell-mediated immunity critically depends on the localization of lymphocytes at sites of infection. While some memory T cells… (More)
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Highly Cited
2013
Highly Cited
2013
Inflammatory bowel disease is an important risk factor for colorectal cancer. We show that sphingosine-1-phosphate (S1P) produced… (More)
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Highly Cited
2012
Highly Cited
2012
Recent studies underscore the importance of myeloid cells in rendering distant organs hospitable for disseminating tumor cells to… (More)
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Highly Cited
2012
Highly Cited
2012
Angiogenesis, the process by which new blood vessels arise from preexisting ones, is critical for embryonic development and is an… (More)
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2012
2012
Millions of platelets are produced each hour by bone marrow (BM) megakaryocytes (MKs). MKs extend transendothelial proplatelet… (More)
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2012
2012
STAT3 plays a crucial role in promoting progression of human cancers, including several types of B-cell lymphoma. However, as a… (More)
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Highly Cited
2011
Highly Cited
2011
Lymphocytes egress from lymphoid organs in response to sphingosine-1-phosphate (S1P); minutes later they migrate from blood into… (More)
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2011
2011
Microglial activation in multiple sclerosis has been postulated to contribute to long-term neurodegeneration during disease… (More)
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2011
2011
Endothelial cell (EC) barrier dysfunction induced by inflammatory agonists is a frequent pathophysiologic event in multiple… (More)
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