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S1PR1 gene

Known as: Sphingosine-1-Phosphate Receptor 1 Gene, D1S3362, edg-1 
This gene plays a role in lipid binding.
National Institutes of Health

Related topics

Related topics

15 relations
Cell AdhesionCell MovementCytoskeletal ModelingG Protein-Coupled Receptor Signaling

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S1PR1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Sphingosine 1-Phosphate Receptor Subtype 1 as a Therapeutic Target for Brain Trauma.
Traumatic brain injury (TBI) provokes secondary pathological mechanisms, including ischemic and inflammatory processes. The new… 
2016
2016
Endocytosis of Ligand‐Activated Sphingosine 1‐Phosphate Receptor 1 Mediated by the Clathrin‐Pathway
The sphingosine 1‐phosphate receptor 1 (S1PR1) is one of five G protein‐coupled receptors activated by the lipid sphingosine 1… 
2015
2015
S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness
ABSTRACT Activation of sphingosine-1-phosphate receptor 1 (S1PR1) plays a key role in repairing endothelial barrier function. We… 
2014
2014
Dynamin 2–dependent endocytosis is required for sustained S1PR1 signaling
The endocytosis regulator dynamin 2 is required for the regulation of S1PR1 internalization and continued S1PR1 signaling in low… 
2012
2012
LPS and TNF-α induce expression of sphingosine-1-phosphate receptor-2 in human microvascular endothelial cells.
2012
2012
Knockdown of the sphingosine-1-phosphate receptor S1PR1reduces pain behaviors induced by local inflammation of the rat sensory ganglion
2012
2012
CCR7/CCL19 Controls Expression of EDG-1 in T Cells*
Background: CCL19 ligand controls signaling events in T cells. Results: CCL19 promotes up-regulation of ERK5 to regulate KLF-2… 
2010
2010
Expression of sphingosine-1-phosphate receptor 1 in mantle cell lymphoma
The distribution and pathological significance of sphingosine-1-phosphate receptor 1 expression are still unclear. In this study… 
2008
2008
Immunohistochemical detection of sphingosine-1-phosphate receptor 1 in vascular and lymphatic endothelial cells
Sphingosine-1-phosphate receptor 1 (S1P1), a receptor for sphingosine-1-phosphate, has been shown to play an important role in… 
Highly Cited
1999
Highly Cited
1999
Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and…
We report here that cultured airway smooth muscle cells contain transcripts of endothelial differentiation gene 1 (EDG-1), a… 
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