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S 2242
Known as:
S-2242
, S2242
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Purines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Antiadenovirus Activities of Several Classes of Nucleoside and Nucleotide Analogues
L. Naesens
,
L. Lenaerts
,
+5 authors
E. Clercq
Antimicrobial Agents and Chemotherapy
2005
Corpus ID: 2556287
ABSTRACT The absence of any formally licensed antiadenovirus drugs and the increasing incidence of life-threatening adenovirus…
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Review
2004
Review
2004
Therapeutic potential of nucleoside/nucleotide analogues against poxvirus infections
E. De Clercq
,
J. Neyts
Reviews in Medical Virology
2004
Corpus ID: 9946701
Several nucleoside and nucleotide analogues have been identified as potent antiviral agents with convincing activity against…
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2001
2001
Efficacy of 2-Amino-7-(1,3-Dihydroxy-2-Propoxymethyl)Purine for Treatment of Vaccinia Virus (Orthopoxvirus) Infections in Mice
J. Neyts
,
E. De Clercq
Antimicrobial Agents and Chemotherapy
2001
Corpus ID: 10647794
ABSTRACT We have previously shown that the N-7 substituted acyclic nucleoside analog 2-amino-7-[1,3-dihydroxy-2-propoxy)methyl…
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1999
1999
Selective activity of various antiviral compounds against HHV-7 infection.
Y. Zhang
,
D. Schols
,
E. De Clercq
Antiviral Research
1999
Corpus ID: 39531326
Highly Cited
1998
Highly Cited
1998
In Vitro and In Vivo Inhibition of Murine Gamma Herpesvirus 68 Replication by Selected Antiviral Agents
J. Neyts
,
E. De Clercq
Antimicrobial Agents and Chemotherapy
1998
Corpus ID: 25782902
ABSTRACT We have evaluated the susceptibility of the murine gamma herpesvirus 68 (MHV-68) to a variety of antiviral agents. The…
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Highly Cited
1997
Highly Cited
1997
Antiviral drug susceptibility of human herpesvirus 8
J. Neyts
,
E. Clercq
Antimicrobial Agents and Chemotherapy
1997
Corpus ID: 33252448
We studied the susceptibility of human herpesvirus 8 (HHV-8) to a number of antiherpesvirus agents. The acyclic nucleoside…
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1997
1997
Phosphorylation of aciclovir, ganciclovir, penciclovir and S2242 by the cytomegalovirus UL97 protein: a quantitative analysis using recombinant vaccinia viruses.
A. Zimmermann
,
D. Michel
,
+5 authors
T. Mertens
Antiviral Research
1997
Corpus ID: 37515275
Highly Cited
1996
Highly Cited
1996
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
Eiichi Kodama
,
S. Shigeta
,
Toshimitsu Suzuki
,
E. Clercq
Antiviral Research
1996
Corpus ID: 22935095
1995
1995
In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine
J. Neyts
,
G. Jähne
,
G. Andrei
,
R. Snoeck
,
Irvin Winkler
,
E. Clercq
Antimicrobial Agents and Chemotherapy
1995
Corpus ID: 12670879
The efficacy of 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine (S2242) was evaluated in several animal models for herpesvirus…
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1994
1994
The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication
J. Neyts
,
G. Andrei
,
+5 authors
E. De Clercq
Antimicrobial Agents and Chemotherapy
1994
Corpus ID: 40826513
2-Amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine (compound S2242) represents the first antivirally active nucleoside analog with…
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