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S-1452

 
National Institutes of Health

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2004
2004
Although thromboxanes (TXs), whose synthesis is regulated by cyclooxygenase (COX), have been suggested to promote inflammation in… Expand
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2001
2001
Increased sensitivity of cough reflex is a fundamental feature of bronchodilator resistant non-productive cough associated with… Expand
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2001
2001
S-1452, a selective thromboxane (Tx) A2 receptor (TP-receptor) antagonist, was evaluated in antigen- and U-46619 (a TxA2 mimetic… Expand
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1996
1996
Oxygen radicals produced by activated neutrophils have been involved in brain injury during ischemia-reperfusion. Platelet… Expand
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1995
1995
Interleukin-8 (IL-8) has been shown to be a chemotactic factor for neutrophils, T-lymphocytes and eosinophils, but it is unknown… Expand
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1995
1995
1. We have examined whether three natural tachykinins, substance P (SP), neurokinin A (NKA) and neurokinin B (NKB) induce an… Expand
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1995
1995
To shed light on the role of thromboxane A2 (TXA2) in renal injury, we evaluated the effects of S-1452, a TXA2 receptor… Expand
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1994
1994
Long-lasting bronchial hyperresponsiveness to i.v. acetylcholine was observed in actively sensitized guinea-pigs after aerosol… Expand
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1993
1993
BACKGROUND AND PURPOSE Arachidonate metabolites have been implicated in the development of cerebral injury after ischemia… Expand
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1992
1992
We examined the effect of a potent thromboxane (Tx) A2 receptor antagonist, calcium (1R, 2S, 3S, 4S)-(5Z)-7-(((phenylsulfonyl… Expand
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