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S-1452

National Institutes of Health

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Highly Cited
2001
Highly Cited
2001
Characterization of increased cough sensitivity after antigen challenge in guinea pigs
Increased sensitivity of cough reflex is a fundamental feature of bronchodilator resistant non‐productive cough associated with… 
Highly Cited
1996
Highly Cited
1996
Role of platelet-activating factor and thromboxane A2 in radical production during ischemia and reperfusion of the rat brain
1996
1996
Possible involvement of endothelial leukotrienes in acetylcholine-induced contraction in rabbit coronary artery.
1995
1995
Bronchial hyperresponsiveness and airway neutrophil accumulation induced by interleukin‐8 and the effect of the thromboxane A2 antagonist S‐1452 in guinea‐pigs
Interleukin‐8 (IL‐8) has been shown to be a chemotactic factor for neutrophils, T‐lymphocytes and eosinophils, but it is unknown… 
1995
1995
Endothelium-dependent contraction induced by acetylcholine in isolated rat renal arteries.
1995
1995
Antiproteinuric effect of a thromboxane receptor antagonist, S-1452, on rat diabetic nephropathy and murine lupus nephritis.
To shed light on the role of thromboxane A2 (TXA2) in renal injury, we evaluated the effects of S-1452, a TXA2 receptor… 
1993
1993
Effect of a Novel Thromboxane A2 Receptor Antagonist, S‐1452, on Postischemic Brain Injury in Rats
Background and Purpose Arachidonate metabolites have been implicated in the development of cerebral injury after ischemia… 
1993
1993
Involvement of thromboxane A2 in bronchial hyperresponsiveness but not lung inflammation induced by bacterial lipopolysaccharide in guinea pigs.
1992
1992
Antiasthmatic activity of a novel thromboxane A2 antagonist, S-1452, in guinea pigs.
We examined the effect of a potent thromboxane (Tx) A2 receptor antagonist, calcium (1R, 2S, 3S, 4S)-(5Z)-7-(((phenylsulfonyl… 
1992
1992
Putative mechanism of hypotensive action of platelet-activating factor in dogs.
We examined the mechanism(s) of hypotensive action of platelet-activating factor (PAF) in anesthetized dogs. PAF (0.5 micrograms… 
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