S-1452
National Institutes of Health
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To separately assess intestinal and hepatic first-pass effects with absorption ratio data, we have established an experimental…
Interleukin‐8 (IL‐8) has been shown to be a chemotactic factor for neutrophils, T‐lymphocytes and eosinophils, but it is unknown…
To shed light on the role of thromboxane A2 (TXA2) in renal injury, we evaluated the effects of S-1452, a TXA2 receptor…
Background and Purpose Arachidonate metabolites have been implicated in the development of cerebral injury after ischemia…
The absorption, distribution, metabolism and excretion of S-1452, a new thromboxane A2 receptor antagonist, were studied after a…