Ring Finger Domain

Known as: Ring Finger Motif, RING Finger Motifs, Ring-Type Zinc Finger Domain 
A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
051019922018

Papers overview

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2008
2008
Polycomb group (PcG) proteins are a set of chromatin-modifying proteins that play a key role in epigenetic gene regulation. The… (More)
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2004
2004
Tumor necrosis factor receptor associated factor 6 (TRAF6) is an important signaling molecule involved in a diverse array of… (More)
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Highly Cited
2001
Highly Cited
2001
Low temperature is one of the most important environmental stimuli that control gene transcription programs and development in… (More)
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Highly Cited
2000
Highly Cited
2000
We previously showed that oncoprotein MDM2 has ubiquitin ligase activity toward tumor suppressor p53. In that paper, we showed… (More)
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Highly Cited
1999
Highly Cited
1999
The N-terminus of MDM2 proto-oncoprotein interacts with p53 and down modulates p53 activity by inhibiting transcriptional… (More)
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1999
1999
Breast cancer 1 (BRCA1) and BRCA1-associated RING domain 1 (BARD1) are multidomain proteins that interact in vivo via their N… (More)
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Highly Cited
1996
Highly Cited
1996
3-hydroxy-3-methylglutaryl-CoA reductase (HMG-R), a key enzyme of sterol synthesis, is an integral membrane protein of the… (More)
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Highly Cited
1996
Highly Cited
1996
Baculovirus inhibitors of apoptosis (IAPs) act in insect cells to prevent cell death. Here we describe three mammalian homologs… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND The cellular mdm2 gene has transforming activity when overexpressed and is amplified in a variety of human tumors. At… (More)
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1995
Highly Cited
1995
TNF receptor-associated factor (TRAF) proteins are candidate signal transducers that associate with the cytoplasmic domains of… (More)
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