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BIRC4 protein, human

Known as: EC6.3.2.-, baculoviral IAP repeat-containing protein-4, human, MIHA protein, human 
Baculoviral IAP repeat-containing protein 4 (497 aa, ~57 kDa) is encoded by the human XIAP gene. This protein plays a role in both protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
X‐linked inhibitor of apoptosis (XIAP) deficiency, caused by mutations in BIRC4, is an immunodeficiency associated with immune… Expand
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Highly Cited
2009
Highly Cited
2009
BackgroundIn a prior randomized phase II trial comparing hyperthermic isolated limb perfusion (HILP) with four different doses of… Expand
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Highly Cited
2008
Highly Cited
2008
BackgroundIsolated limb infusion (ILI) is a recently described minimally invasive technique developed in Australia for delivering… Expand
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Highly Cited
2006
Highly Cited
2006
The homeostasis of the immune response requires tight regulation of the proliferation and apoptosis of activated lymphocytes. In… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE To determine in a randomized prospective multi-institutional trial whether the addition of tumor necrosis factor alpha… Expand
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Highly Cited
2000
Highly Cited
2000
Several endogenous or viral inhibitors of apoptosis, including Bcl-2, Bcl-xL, FLIP, p35, and CrmA, have been shown to be cleaved… Expand
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Highly Cited
1999
Highly Cited
1999
The inhibitor-of-apoptosis (IAP) family of proteins, originally identified in baculoviruses, regulate programmed cell death in a… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT The gene encoding human IAP-like protein (hILP) is one of several mammalian genes with sequence homology to the… Expand
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Highly Cited
1998
Highly Cited
1998
The balance between the inductive signals and endogenous anti-apoptotic mechanisms determines whether or not programmed cell… Expand
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Highly Cited
1996
Highly Cited
1996
The baculovirus inhibitor of apoptosis gene, iap, can impede cell death in insect cells. Here we show that iap can also prevent… Expand
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