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Rifampin

Known as: Benemycin, Rifampin [Chemical/Ingredient], 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV 
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the newest version, are the only World Health… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Global control of tuberculosis is hampered by slow, insensitive diagnostic methods, particularly for the detection of… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT Current nucleic acid amplification methods to detect Mycobacterium tuberculosis are complex, labor-intensive, and… Expand
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Highly Cited
2002
Highly Cited
2002
The search for new TB drugs that rapidly and effectively sterilize the tissues and are thus able to shorten the duration of… Expand
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Highly Cited
2001
Highly Cited
2001
Intestinal P-glycoprotein, which is encoded by the MDR1 gene, plays an important role in the absorption and presystemic… Expand
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Highly Cited
1999
Highly Cited
1999
Recent data point to the contribution of P-glycoprotein (P-gp) to digoxin elimination. On the basis of clinical observations of… Expand
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Highly Cited
1998
Highly Cited
1998
CONTEXT Rifampin-containing regimens are able to cure staphylococcal implant-related infections based on in vitro and in vivo… Expand
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Highly Cited
1992
Highly Cited
1992
Enzymes within the P450IIIA (CYP3A) subfamily appear to account for significant "first pass" metabolism of some drugs in the… Expand
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Highly Cited
1991
Highly Cited
1991
OBJECTIVE To determine the median response time to therapy with vancomycin alone or with vancomycin plus rifampin in patients… Expand
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Highly Cited
1991
Highly Cited
1991
ALT = serum alanine aminotransferase; AST serum aspartate aminotransferase; BIU bilirubin; EMB ethambutol; INH isoniazid; NSM not… Expand
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