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Rifampin

Known as: Benemycin, Rifampin [Chemical/Ingredient], 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV 
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Global control of tuberculosis is hampered by slow, insensitive diagnostic methods, particularly for the detection of… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT Current nucleic acid amplification methods to detect Mycobacterium tuberculosis are complex, labor-intensive, and… Expand
Highly Cited
2002
Highly Cited
2002
The search for new TB drugs that rapidly and effectively sterilize the tissues and are thus able to shorten the duration of… Expand
Highly Cited
2001
Highly Cited
2001
Intestinal P-glycoprotein, which is encoded by the MDR1 gene, plays an important role in the absorption and presystemic… Expand
Highly Cited
1999
Highly Cited
1999
Recent data point to the contribution of P-glycoprotein (P-gp) to digoxin elimination. On the basis of clinical observations of… Expand
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Review
1999
Review
1999
  • F. Guengerich
  • Annual review of pharmacology and toxicology
  • 1999
  • Corpus ID: 36331311
Cytochrome P-450 (P-450) 3A4 is the most abundant P-450 expressed in human liver and small intestine. P-450 3A4 contributes to… Expand
Highly Cited
1998
Highly Cited
1998
CONTEXT Rifampin-containing regimens are able to cure staphylococcal implant-related infections based on in vitro and in vivo… Expand
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Review
1997
Review
1997
  • M. Corbel
  • Emerging infectious diseases
  • 1997
  • Corpus ID: 11017623
Brucellosis remains a major zoonosis worldwide. Although many countries have eradicated Brucella abortus from cattle, in some… Expand
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Highly Cited
1993
Highly Cited
1993
Control of tuberculosis is threatened by widespread emergence of drug resistance in Mycobacterium tuberculosis. Understanding the… Expand
Highly Cited
1991
Highly Cited
1991
ALT = serum alanine aminotransferase; AST serum aspartate aminotransferase; BIU bilirubin; EMB ethambutol; INH isoniazid; NSM not… Expand