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- Publications
- Influence
Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′, 5′-Cyclic GMP
- S. Pino, Giovanna Costanzo, A. Giorgi, J. Šponer, J. Sponer, E. Mauro
- Chemistry, Computer Science
- Entropy
- 3 December 2013
TLDR
A Novel Synthesis of Biomolecular Precursors
- R. Saladino, C. Crestini, Fabiana Ciciriello, Giovanna Costanzo, R. Negri, E. Mauro
- Chemistry
- 1 July 2004
We discuss the role of formamide, a product of hydrolysis of hydrogen cyanide (HCN), as precursor of relevant components of nucleic acids in prebiotic conditions and describe the efficient synthesis… Expand
Rifampicin Sensitivity of the Components of DNA-dependent RNA Polymerase
- E. Mauro, L. Snyder, P. Marino, A. Lamberti, A. Coppo, G. Tocchini-Valentini
- Chemistry, Medicine
- Nature
- 10 May 1969
The phosphocellulose component of RNA polymerase binds the first nucleotide when synthesis of an RNA chain is initiated
Telomeric transcriptional silencing in a natural context
- M. A. Vega-Palas, S. Venditti, E. Mauro
- Biology, Medicine
- Nature Genetics
- 1 March 1997
The Effects of Borate Minerals on the Synthesis of Nucleic Acid Bases, Amino Acids and Biogenic Carboxylic Acids from Formamide
- R. Saladino, M. Barontini, Cristina Cossetti, E. Mauro, C. Crestini
- Medicine, Chemistry
- Origins of Life and Evolution of Biospheres
- 19 March 2011
The thermal condensation of formamide in the presence of mineral borates is reported. The products afforded are precursors of nucleic acids, amino acids derivatives and carboxylic acids. The… Expand
Gene expression pathways induced by axotomy and decentralization of rat superior cervical ganglion neurons
- A. Signore, V. Sanctis, E. Mauro, R. Negri, C. Perrone-Capano, P. Paggi
- Biology, Medicine
- The European journal of neuroscience
- 1 January 2006
To identify genes potentially involved in remodelling synaptic connections, we induced the temporary detachment of pre‐ and post‐synaptic elements by axotomy or denervation of rat superior cervical… Expand
Catalytic effects of Murchison Material: Prebiotic Synthesis and Degradation of RNA Precursors
- R. Saladino, C. Crestini, Cristina Cossetti, E. Mauro, D. Deamer
- Chemistry, Medicine
- Origins of Life and Evolution of Biospheres
- 12 April 2011
Mineral components of the Murchison meteorite were investigated in terms of potential catalytic effects on synthetic and hydrolytic reactions related to ribonucleic acid. We found that the mineral… Expand
Chemical method for DNA sequence determination from the 5'-extremity on PCR amplified fragments
- R. Negri, S. Ferraboli, S. Barlati, E. Mauro
- Biology, Medicine
- Nucleic Acids Res.
- 11 January 1994
TLDR
Current Advances in Prebiotic Chemistry Under Space Conditions
- E. Carota, G. Botta, L. Rotelli, E. Mauro, R. Saladino
- Chemistry
- 1 September 2015
About a Formamide-Based Origin of Informational Polymers: Syntheses of Nucleobases and Favourable Thermodynamic Niches for Early Polymers
- R. Saladino, C. Crestini, Fabiana Ciciriello, Giovanna Costanzo, E. Mauro
- Chemistry, Medicine
- Origins of Life and Evolution of Biospheres
- 29 November 2006
Formamide NH2CHO chemistry provides a unitary frame into which several pieces of the origin-of-life puzzle may be adjusted. Synthetic processes were uncovered which, starting from formamide and… Expand