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Ribosyldihydronicotinamide Dehydrogenase [Quinone]

Known as: Ribosyldihydronicotinamide Dehydrogenase, NRH Dehydrogenase [Quinone] 2, NQO2 
Ribosyldihydronicotinamide dehydrogenase [quinone] (231 aa, ~26 kDa) is encoded by the human NQO2 gene. This protein is involved in the metabolism of… 
National Institutes of Health

Related topics

Related topics

7 relations
CytoplasmEnzyme GeneNQO2 geneOxidation-Reduction

Papers overview

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Highly Cited
2011
Highly Cited
2011
Insights into the redox cycle of human quinone reductase 2
Abstract NRH:quinone oxidoreductase 2 (QR2) is a cytosolic enzyme that catalyzes the reduction of quinones, such as menadione and… 
Highly Cited
2010
Highly Cited
2010
Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer.
Highly Cited
2008
Highly Cited
2008
Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Melatonin exerts its biological effects through at least two transmembrane G-protein-coupled receptors, MT1 and MT2, and a lower… 
Review
2007
Review
2007
Melatonin as a naturally occurring co‐substrate of quinone reductase‐2, the putative MT3 melatonin membrane receptor: hypothesis and significance
Abstract:  The nature of the MT3 melatonin receptor/binding site has been a long pondered mystery for scientists. Even though it… 
Highly Cited
2006
Highly Cited
2006
An investigation of gold adsorption from a binary mixture with selective mesoporous silica adsorbents.
Gold-selective adsorbents were prepared from mesoporous MCM-41 silica by grafting organic amine groups (i.e., RNH2, R2NH, and R3N… 
Highly Cited
2002
Highly Cited
2002
Discovery of novel targets of quinoline drugs in the human purine binding proteome.
The quinolines have been used in the treatment of malaria, arthritis, and lupus for many years, yet the precise mechanism of… 
Highly Cited
2001
Highly Cited
2001
Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2 .
Highly Cited
2001
Highly Cited
2001
Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis.
We report the case of a 66-year-old male with ulcerative colitis diagnosed in 1987, who had been treated with azathioprine (AZA… 
Review
2000
Review
2000
Structure-function studies of DT-diaphorase (NQO1) and NRH: quinone oxidoreductase (NQO2).
Highly Cited
1996
Highly Cited
1996
Expression and Characterization of the Flavoprotein Subcomplex Composed of 50-kDa (NQO1) and 25-kDa (NQO2) Subunits of the Proton-translocating NADH-Quinone Oxidoreductase of Paracoccus denitrificans…
This study reports the expression of the flavoprotein (FP) subcomplex of the proton-translocating NADH-quinone oxidoreductase… 
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