Recombinant melatonin

Known as: Melatonin, Therapeutic Melatonin 
A therapeutic chemically synthesized form of the pineal indole melatonin with antioxidant properties. The pineal synthesis and secretion of melatonin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
051019882017

Related topics

Related topics

2 relations

Broader (1)

Melatonin
Melatonin Measurement

Related mentions per year

Related mentions per year

1958-2018
1960198020002020
Recombinant melatonin
Melatonin
Melatonin Measurement

Papers overview

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Highly Cited
2012
Highly Cited
2012
Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes
Genome-wide association studies have revealed that common noncoding variants in MTNR1B (encoding melatonin receptor 1B, also… (More)
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Highly Cited
2009
Highly Cited
2009
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
Genome-wide association studies have shown that variation in MTNR1B (melatonin receptor 1B) is associated with insulin and… (More)
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Highly Cited
2007
Highly Cited
2007
Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease.
The pineal hormone melatonin is involved in the regulation of circadian rhythms and feeds back to the central biological clock… (More)
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Highly Cited
2004
Highly Cited
2004
Melatonin signaling dysfunction in adolescent idiopathic scoliosis.
STUDY DESIGN In vitro assays were performed with bone-forming cells isolated from 41 patients with adolescent idiopathic… (More)
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Highly Cited
2001
Highly Cited
2001
Direct action of melatonin in human granulosa-luteal cells.
The direct involvement of melatonin in modulation of ovarian steroidogenesis, the high levels of melatonin found in human… (More)
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Highly Cited
1999
Highly Cited
1999
Identification of highly elevated levels of melatonin in bone marrow: its origin and significance.
Bone marrow is an important tissue in generation of immunocompetent and peripheral blood cells. The progenitors of hematopoietic… (More)
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Highly Cited
1998
Highly Cited
1998
Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms.
This study demonstrates the involvement of the MT2 (Mel1b) melatonin receptor in mediating phase advances of circadian activity… (More)
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Highly Cited
1995
Highly Cited
1995
Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor.
A G protein-coupled receptor for the pineal hormone melatonin was recently cloned from mammals and designated the Mel1a melatonin… (More)
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Highly Cited
1995
Highly Cited
1995
Melatonin receptors are for the birds: Molecular analysis of two receptor subtypes differentially expressed in chick brain
Two receptors (CKA and CKB) of the G protein-coupled melatonin receptor family were cloned from chick brain. CKA encodes a… (More)
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Highly Cited
1994
Highly Cited
1994
Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses.
The pineal hormone melatonin regulates seasonal reproductive function and modulates circadian rhythms in mammals. We now report… (More)
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