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Recombinant Tumor Necrosis Factor-Beta

Known as: Tumor Necrosis Factor-Beta, Lymphotoxin, TNF beta 
A recombinant agent, which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-beta (TNF-beta). Produced… Expand
National Institutes of Health

Papers overview

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Highly Cited
1995
Highly Cited
1995
Recombinant TNF and lymphotoxin trigger the apoptotic death of normal mouse and human T lymphocyte blasts in vitro. This… Expand
Highly Cited
1992
Highly Cited
1992
The three-dimensional structure of recombinant human lymphotoxin (residues 24-171 of the mature protein) has been determined by x… Expand
Highly Cited
1991
Highly Cited
1991
The cytotoxic effect of recombinant human cytokines was tested on glial cells cultured from mature bovine brain. Lymphotoxin (LT… Expand
Highly Cited
1989
Highly Cited
1989
We have analyzed the ability of highly purified preparations of human NK cells to produce CSF. NK cells, purified by negative… Expand
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Highly Cited
1988
Highly Cited
1988
The vascular endothelium plays an important role in fibrinolysis by producing tissue-type plasminogen activator (t-PA) and… Expand
Highly Cited
1987
Highly Cited
1987
Recombinant human lymphotoxin (LT) was compared with recombinant human tumor necrosis factor (TNF) for direct actions on cultured… Expand
Highly Cited
1987
Highly Cited
1987
Myeloma cells destroy bone by producing an osteoclast-stimulating factor that has chemical and biological characteristics similar… Expand
Highly Cited
1987
Highly Cited
1987
We report here a comparative study of the effects of several cytokines known to affect myeloid cell differentiation on functional… Expand
Highly Cited
1984
Highly Cited
1984
Human tumour necrosis factor has about 30% homology in its amino acid sequence with lymphotoxin, a lymphokine that has similar… Expand
Highly Cited
1984
Highly Cited
1984
A chemically-synthesized gene and natural complementary DNA coding for human lymphotoxin were isolated and engineered for… Expand