Skip to search formSkip to main contentSkip to account menu

Recombinant Tumor Necrosis Factor-Beta

Known as: Tumor Necrosis Factor-Beta, Lymphotoxin, TNF beta 
A recombinant agent, which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-beta (TNF-beta). Produced… 
National Institutes of Health

Related topics

Related topics

3 relations
LTA geneLymphotoxin-Alpha, humanTumor Necrosis Factor-Beta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts.
Recombinant TNF and lymphotoxin trigger the apoptotic death of normal mouse and human T lymphocyte blasts in vitro. This… 
Highly Cited
1991
Highly Cited
1991
Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin.
The cytotoxic effect of recombinant human cytokines was tested on glial cells cultured from mature bovine brain. Lymphotoxin (LT… 
Highly Cited
1990
Highly Cited
1990
Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients.
Serum ultrafiltrates (SUF) from human patients with different types of cancer contain a blocking factor (BF) that inhibits the… 
Highly Cited
1988
Highly Cited
1988
Regulation of human lung fibroblast glycosaminoglycan production by recombinant interferons, tumor necrosis factor, and lymphotoxin.
Mononuclear cells may be important regulators of fibroblast glycosaminoglycan (GAG) biosynthesis. However, the soluble factors… 
Highly Cited
1988
Highly Cited
1988
Effects of recombinant tumor necrosis factor, lymphotoxin, and immune interferon on proliferation and differentiation of enriched hematopoietic precursor cells.
We compared the effects of recombinant (r) tumor necrosis factor (TNF) and lymphotoxin (rLT) on in vitro colony formation by… 
Highly Cited
1987
Highly Cited
1987
Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.
Recombinant human lymphotoxin (LT) was compared with recombinant human tumor necrosis factor (TNF) for direct actions on cultured… 
Highly Cited
1987
Highly Cited
1987
Immune interferon enhances functional properties of human granulocytes: role of Fc receptors and effect of lymphotoxin, tumor necrosis factor, and granulocyte-macrophage colony-stimulating factor.
We report here a comparative study of the effects of several cytokines known to affect myeloid cell differentiation on functional… 
Highly Cited
1987
Highly Cited
1987
Lymphotoxin is an important T cell-derived growth factor for human B cells.
Two different assays for B cell growth factors (BCGF) and an antibody against lymphotoxin were used to show that the presence of… 
Highly Cited
1984
Highly Cited
1984
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin
Human tumour necrosis factor has about 30% homology in its amino acid sequence with lymphotoxin, a lymphokine that has similar… 
Highly Cited
1984
Highly Cited
1984
Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity
A chemically-synthesized gene and natural complementary DNA coding for human lymphotoxin were isolated and engineered for… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)