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Recombinant Tumor Necrosis Factor-Beta

Known as: Tumor Necrosis Factor-Beta, Lymphotoxin, TNF beta 
A recombinant agent, which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-beta (TNF-beta). Produced… Expand
National Institutes of Health

Related topics

Related topics

3 relations
LTA geneLymphotoxin-Alpha, humanTumor Necrosis Factor-Beta

Papers overview

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Highly Cited
2001
Highly Cited
2001
Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue.
A recombinant antibody-lymphotoxin-alpha fusion protein induced an adaptive immune response protecting mice from melanoma… Expand
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Highly Cited
1995
Highly Cited
1995
Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts.
Recombinant TNF and lymphotoxin trigger the apoptotic death of normal mouse and human T lymphocyte blasts in vitro. This… Expand
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Highly Cited
1991
Highly Cited
1991
Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin.
The cytotoxic effect of recombinant human cytokines was tested on glial cells cultured from mature bovine brain. Lymphotoxin (LT… Expand
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Highly Cited
1989
Highly Cited
1989
Production of hematopoietic colony-stimulating factors by human natural killer cells
We have analyzed the ability of highly purified preparations of human NK cells to produce CSF. NK cells, purified by negative… Expand
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  • table I
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Highly Cited
1988
Highly Cited
1988
tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo
The vascular endothelium plays an important role in fibrinolysis by producing tissue-type plasminogen activator (t-PA) and… Expand
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Highly Cited
1987
Highly Cited
1987
Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.
Recombinant human lymphotoxin (LT) was compared with recombinant human tumor necrosis factor (TNF) for direct actions on cultured… Expand
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Highly Cited
1987
Highly Cited
1987
Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells.
Myeloma cells destroy bone by producing an osteoclast-stimulating factor that has chemical and biological characteristics similar… Expand
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Review
1987
Review
1987
Effects of tumour necrosis factor and related cytokines on vascular endothelial cells.
  • J. Pober
  • Ciba Foundation symposium
  • 1987
    • Corpus ID: 24809281
Tumour necrosis factor (TNF) and related cytokines have been found to alter the phenotype of vascular endothelial cells so as to… Expand
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Highly Cited
1984
Highly Cited
1984
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin
Human tumour necrosis factor has about 30% homology in its amino acid sequence with lymphotoxin, a lymphokine that has similar… Expand
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Highly Cited
1984
Highly Cited
1984
Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity
A chemically-synthesized gene and natural complementary DNA coding for human lymphotoxin were isolated and engineered for… Expand
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