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Recombinant MAGE-3.1 Antigen

Known as: MAGE-3, MAGE-3.1, MAGEA3 
A recombinant tumor-specific melanoma antigen. Vaccination with recombinant MAGE-3.1 antigen may induce a host immune response against MAGE… 
National Institutes of Health

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MAGEA3 geneMAGEA3 protein, humanMAGEA3 wt AlleleNCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Long Term Transcriptional Reactivation of Epigenetically Silenced Genes in Colorectal Cancer Cells Requires DNA Hypomethylation and Histone Acetylation
Epigenetic regulation of genes involves the coordination of DNA methylation and histone modifications to maintain transcriptional… 
2003
2003
Vaccine-induced CD8+ T-cell responses to MAGE-3 correlate with clinical outcome in patients with melanoma.
PURPOSE Vaccine-induced antitumor CD8+ T-cell responses are believed to play an important role in increasing resistance to… 
2002
2002
Expression of cancer/testis antigens in cutaneous T cell lymphomas
Cancer/testis‐antigens (CTA), a novel and expanding family of immunogenic proteins detected by serological screening of… 
2002
2002
Development of HLA‐A2402/Kb transgenic mice
HLA‐transgenic mice have been developed to facilitate studies of HLA‐restricted cytotoxic responses, e.g., for the identification… 
Highly Cited
2000
Highly Cited
2000
Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes
The level of expression of melanoma antigens (MA) may modulate the host immunologic response. Thus, the accurate measurement of… 
2000
2000
Efficient expression of the tumor-associated antigen MAGE-3 in human dendritic cells, using an avian influenza virus vector.
Dendritic cells (DCs) are the most potent inducers of immune reactions. Genetically modified DCs, which express tumor-associated… 
Highly Cited
1997
Highly Cited
1997
Analysis of the T cell response to tumor and viral peptide antigens by an IFNγ‐ELISPOT assay
We have established a sensitive ELISPOT assay measuring interferon γ (IFN γ) release on a single‐cell basis to detect influenza… 
1997
1997
Induction of antibody response to human tumor antigens by gene therapy using a fusigenic viral liposome vaccine
Development of effective cancer vaccines would help prevent and control tumor progression. A novel approach of immunizing against… 
1996
1996
MAGE‐1 and MAGE‐3 or ‐6 expression in neuroblastoma‐related pediatric solid tumors
MAGE‐1 and MAGE‐3 or ‐6 are genes encoding melanoma‐rejection antigens recognized by cytotoxic T lymphocytes in an HLA‐AI… 
1996
1996
Characterization of antigenic peptides presented by HLA‐B44 molecules on tumor cells expressing the gene MAGE‐3
The amino acid sequence of the protein encoded by the gene MAGE‐3was screened for peptides containing the binding motif for HLA… 
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