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MAGEA3 protein, human

Known as: melanoma antigen, family A, 3 protein, human, melanoma antigen-3, human, MAGEA3 
Melanoma-associated antigen 3 (314 aa, ~35 kDa) is encoded by the human MAGEA3 gene. This protein may be involved in embryological development.
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

Antigens, NeoplasmNeoplasm Proteins
Immune System ProcessesMAGEA3 geneMAGEA3 wt AlleleRecombinant MAGE-3.1 Antigen

Papers overview

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2011
2011
BORIS Binding to the Promoters of Cancer Testis Antigens, MAGEA2, MAGEA3, and MAGEA4, Is Associated with Their Transcriptional Activation in Lung Cancer
Purpose: Aim of this study was to determine whether BORIS (Brother of the Regulator of Imprinted Sites) is a regulator of MAGEA2… 
Highly Cited
2002
Highly Cited
2002
The Production of a New MAGE-3 Peptide Presented to Cytolytic T Lymphocytes by HLA-B40 Requires the Immunoproteasome
By stimulating human CD8+ T lymphocytes with autologous dendritic cells infected with an adenovirus encoding MAGE-3, we obtained… 
Review
2002
Review
2002
Evaluation of MAGE-1 and MAGE-3 as tumour-specific markers to detect blood dissemination of hepatocellular carcinoma cells
The members of MAGE gene family are highly expressed in human hepatocellular carcinoma (HCC). In the present study, we tested the… 
Highly Cited
2000
Highly Cited
2000
Expression of cancer testis genes in human brain tumors.
Cancer-testis (CT) genes are expressed in a variety of human cancers but not in normal tissues, except for testis tissue, and… 
Highly Cited
1999
Highly Cited
1999
A newly identified MAGE‐3‐derived epitope recognized by HLA‐A24‐restricted cytotoxic T lymphocytes
Five MAGE‐3‐derived peptides carrying an HLA‐A24‐binding motif were synthesized. Binding capacity of these peptides was analyzed… 
Highly Cited
1997
Highly Cited
1997
Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients.
The MAGE-3 gene is a member of a multigene family that is selectively expressed by subsets of different human tumor types… 
Highly Cited
1997
Highly Cited
1997
MAGE-3 immunoreactivity in formalin-fixed, paraffin-embedded primary and metastatic melanoma: frequency and distribution.
Monoclonal antibody 57B specifically detects MAGE-3 gene protein expression. MAGE-derived peptides are recognized by CD8+ T cells… 
Highly Cited
1997
Highly Cited
1997
Expression of MAGE genes in ocular melanoma during progression from primary to metastatic disease
Primary melanomas that form within the eye have a unique pattern of disease progression as compared with melanomas that form… 
Highly Cited
1994
Highly Cited
1994
A peptide encoded by human gene MAGE‐3 and presented by HLA‐A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE‐3
The human MAGE‐3 gene is expressed in many tumors of several histological types but it is silent in normal tissues, with the… 
Highly Cited
1993
Highly Cited
1993
Transduction of human melanoma cell lines with the human interleukin-7 gene using retroviral-mediated gene transfer: comparison of immunologic properties with interleukin-2.
Two human melanoma cell lines were transduced with the human interleukin (IL)-7 and IL-2 genes using retroviral-mediated gene… 
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