Receptors, Interleukin-8

Known as: Interleukin-8 Receptor, IL-8 Receptors, Receptors, IL8 
Cell surface receptors that are specific for INTERLEUKIN-8. Two specific receptor subtypes (type A and B) have been found and bind IL-8 with high… (More)
National Institutes of Health

Related topics

Related topics

14 relations
C-X-C Chemokine Receptor Type 1, humanC-X-C Chemokine Receptor Type 2, humanChemotaxisCytokine Receptor Gene
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Interleukin 8 Receptor Deficiency Confers Susceptibility to Acute Experimental Pyelonephritis and May Have a Human Counterpart
Neutrophils migrate to infected mucosal sites that they protect against invading pathogens. Their interaction with the epithelial… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2.
Two monoclonal antibodies, anti-IL8R1 and anti-IL8R2, raised against both interleukin 8 receptors (IL-8R) of human neutrophils… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the…
Interleukin-8 (IL-8), growth-related oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2 (NAP-2), epithelial… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential.
The differential expression of chemokine receptors may be an important mechanism for the regulation of T cell migration. To test… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
IL-8 induces neutrophil chemotaxis predominantly via type I IL-8 receptors.
IL-8 is a potent proinflammatory cytokine that has a key role in the recruitment and activation of neutrophils during… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.
Amino acid deletion and mutagenesis experiments have indicated that the sequences Glu-Leu-Arg (ELR) preceding the first cysteine… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri.
Viruses are known to acquire and modify the genes of their hosts to attain a survival advantage in the host environment… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Characterization of two high affinity human interleukin-8 receptors.
Interleukin 8 (IL-8) and melanocyte growth-stimulatory activity/gro (MGSA) are structurally related proinflammatory cytokines… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Structure and functional expression of a human interleukin-8 receptor.
Interleukin-8 (IL-8) is a member of a family of pro-inflammatory cytokines. Although the best characterized activities of IL-8… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Cloning of complementary DNA encoding a functional human interleukin-8 receptor.
Interleukin-8 (IL-8) is an inflammatory cytokine that activates neutrophil chemotaxis, degranulation, and the respiratory burst… (More)
Is this relevant?