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Rab GTPases in Endocytosis Pathway

Known as: Rab GTPases Mark Targets in the Endocytotic Machinery 
The eukaryotic cell contains compartments with distinct functions bounded by lipid bilayer membranes. The movement of membrane vesicles between these… Expand
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Summary The Rab GTPases recruit peripheral membrane proteins to intracellular organelles. These Rab effectors typically mediate… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Neurons require highly specialized intracellular membrane trafficking, especially at synapses. Rab GTPases are… Expand
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Highly Cited
2011
Highly Cited
2011
Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that can replicate within infected macrophages. The ability of M… Expand
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2011
2011
Exo-endocytotic cycling of synaptic vesicles (SVs) is one of the most intensely studied membrane trafficking pathways. It is… Expand
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Highly Cited
2010
Highly Cited
2010
Post-translationally isoprenylated proteins represent major hubs in most membrane-connected signaling networks. GDP dissociation… Expand
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Highly Cited
2006
Highly Cited
2006
Rab GTPases regulate membrane trafficking by cycling between inactive (GDP-bound) and active (GTP-bound) conformations. The… Expand
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Highly Cited
2005
Highly Cited
2005
Rab GTPases regulate all stages of membrane trafficking, including vesicle budding, cargo sorting, transport, tethering and… Expand
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Review
2004
Review
2004
Rab GTPases are key to membrane-trafficking events in eukaryotic cells, and human cells contain more than 60 Rab proteins that… Expand
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Review
2004
Review
2004
The remarkable degree of specificity with which Rab GTPases recognise distinct subsets of intracellular membranes forms the basis… Expand
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Review
2001
Review
2001
SummaryThe Rab family is part of the Ras superfamily of small GTPases. There are at least 60 Rab genes in the human genome, and a… Expand
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