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RXRA gene

Known as: nuclear receptor subfamily 2 group B member 1, NR2B1, RETINOID X RECEPTOR, ALPHA 
This gene plays a role in transcriptional regulation and in the retinoid response pathway.
National Institutes of Health

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Biologic DevelopmentCell Differentiation processCell ProliferationCholesterol Homeostasis

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RXRA wt Allele

Papers overview

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2018
2018
ENHO, RXRA, and LXRA polymorphisms and dyslipidaemia, related comorbidities and survival in haemodialysis patients
BackgroundThe energy homeostasis-associated gene (ENHO), retinoid X receptor alpha gene (RXRA), and liver X receptor alpha gene… 
2015
2015
Absence of natural intracellular retinoids in mouse bone marrow cells and implications for PML-RARA transformation
The X-RARA fusion proteins have reduced sensitivity to all-trans-retinoic acid (ATRA), and have been proposed to act by… 
2015
2015
Effects of Low-Dose Diethylstilbestrol Exposure on DNA Methylation in Mouse Spermatocytes
Evidence from previous studies suggests that the male reproductive system can be disrupted by fetal or neonatal exposure to… 
Review
2015
Review
2015
De novo 9q gain in an infant with tetralogy of Fallot with absent pulmonary valve: Patient report and review of congenital heart disease in 9q duplication syndrome
Genomic disruptions, altered epigenetic mechanisms, and environmental factors contribute to the heterogeneity of congenital heart… 
2014
2014
Genomic Deletions of RXRA-COL5A1, FAM46A-IBTK, HS3ST3B1-PMP22, and GRIA4 in Familial Keratoconus Patients
2013
2013
Genetic variations of NR1I3 and NR2B1 in Asian populations.
Several nuclear receptors are being increasingly recognized for their role as master xenosensors. Among them, CAR-RXR… 
2013
2013
Pharmacogenetic effects of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4α) on docetaxel disposition in Chinese nasopharyngeal cancer patients
This exploratory study was aimed at elucidating the pharmacogenetics of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4… 
2009
2009
Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.
AIMS The modulation of the intestinal expression of detoxifying proteins by relevant transcription factors, intracellular… 
1994
1994
Genetic linkage analysis of the Ak1, Col5a1, Epb7.2, Fpgs, Grp78, Pbx3, and Notch1 genes in the region of mouse chromosome 2 homologous to human chromosome 9q.
The genes for adenylate kinase-1 (AK1), folyl polyglutamate synthetase (FPGS), the collagen pro alpha 1(V) chain (COL5A1… 
1993
1993
Localization of the retinoid X receptor alpha gene (RXRA) to chromosome 9q34
The retinoid X receptor α is one of a number of retinoic acid receptors which are members of the steroid/thyroid hormone… 
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