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RXRA wt Allele

Known as: NR2B1, RXRA, Retinoid X Receptor, Alpha wt Allele 
Human RXRA wild-type allele is located in the vicinity of 9q34.3 and is approximately 39 kb in length. This allele, which encodes retinoic acid… 
National Institutes of Health

Related topics

Related topics

26 relations
9q34.3Adipocytokine Signaling PathwayBiologic DevelopmentCARM1 Transcription Regulation Pathway

Broader (1)

RXRA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract 3627: Validation of PPARG and RXRA as drivers of bladder cancer
A subset of muscle-invasive bladder cancer (BLCA) is typified by PPARG pathway activation. PPARG focal gene amplification occurs… 
2014
2014
Inhibition of IκB kinase-β and IκB kinase-α by heterocyclic adamantyl arotinoids.
2013
2013
Pharmacogenetics of CYP1A2 activity and inducibility in smokers and exsmokers
Background There is a high interindividual variability in cytochrome P4501A2 (CYP1A2) activity and in its inducibility by smoking… 
2013
2013
Genetic variations of NR1I3 and NR2B1 in Asian populations.
Several nuclear receptors are being increasingly recognized for their role as master xenosensors. Among them, CAR-RXR… 
2013
2013
Pharmacogenetic effects of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4α) on docetaxel disposition in Chinese nasopharyngeal cancer patients
This exploratory study was aimed at elucidating the pharmacogenetics of regulatory nuclear receptors (PXR, CAR, RXRα and HNF4… 
Review
2012
Review
2012
Advances in drug design with RXR modulators
Introduction: Retinoid X receptors (subtypes RXRα or NR2B1, RXRβ or NR2B2 and RXRγ or NR2B3, which originate from three distinct… 
2012
2012
Effects of time culture and prototypical cytochrome P450 3A (CYP3A) inducers on CYP2B22, CYP2C, CYP3A and nuclear receptor (NR) mRNAs in long-term cryopreserved pig hepatocytes (CPHs).
In the present study, transcriptional and post-translational effects of culturing time and prototypical cytochrome P450 3A (CYP3A… 
Highly Cited
2004
Highly Cited
2004
A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer.
The X-ray crystal structure of the human constitutive androstane receptor (CAR, NR1I3)/retinoid X receptor alpha (RXRalpha, NR2B1… 
2003
2003
Transcriptional control of the human CYP3A4 gene
CYP3A4 is the most abundant P450 enzyme expressed in the human liver and it is responsible for the metabolism of approximately 50… 
Highly Cited
2001
Highly Cited
2001
Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
Cytochromes P450 (P450s) are involved in the oxidative metabolism of a plethora of structurally unrelated compounds, including… 
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