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RWJ-333369

Known as: (S)-(1-2-chlorophenyl)-1,2-ethanediol 2-carbamate, RWJ 333369, RWJ333369 
National Institutes of Health

Papers overview

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2011
2011
Carisbamate (RWJ-333369) inhibits glutamate transmission in the granule cell of the dentate gyrus
2009
2009
Evaluation of Carisbamate for the Treatment of Migraine in a Randomized, Double‐Blind Trial
Objective.— This study explored the dose‐response relationship of carisbamate administered at doses of 100 mg per day, 300 mg per… 
2009
2009
Investigation of the effects of the novel anticonvulsant compound carisbamate (RWJ‐333369) on rat piriform cortical neurones in vitro
Background and purpose:  Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces… 
2009
2009
Pharmacokinetics of carisbamate (RWJ‐333369) in healthy Japanese and Western subjects
Purpose:  To compare the pharmacokinetics of carisbamate (RWJ‐333369) in healthy Japanese and Western adults, and to… 
2008
2008
Tramadol and several anticonvulsants synergize in attenuating nerve injury-induced allodynia
2008
2008
The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons
2007
2007
The Absorption, Metabolism, and Excretion of the Novel Neuromodulator RWJ-333369 (1,2-Ethanediol, [1-2-Chlorophenyl]-, 2-carbamate, [S]-) in Humans
RWJ-333369 (1,2-ethanediol, [1-2-chlorophenyl]-, 2-carbamate, [S]-; CAS Registry Number 194085-75-1) is a novel neuromodulator in… 
2007
2007
Metabolism and Excretion of RWJ-333369 [1,2-Ethanediol, 1-(2-Chlorophenyl)-, 2-carbamate, (S)-] in Mice, Rats, Rabbits, and Dogs
The in vivo metabolism and excretion of RWJ-333369 [1,2-ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (S)-], a novel… 
2006
2006
Pharmacokinetic Interaction Study between the New Antiepileptic and CNS Drug RWJ‐333369 and Carbamazepine in Healthy Adults
Summary:  Purpose: To characterize the possible pharmacokinetic interaction between the new antiepileptic and CNS drug RWJ‐333369… 
2006
2006
RWJ-333369. Antiepileptic drug treatment of migraine
RWJ-333369 (YKP-509) is a novel, orally active neuromodulator. The compound displayed neuroprotective effects in a rat model of… 
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