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RTKN gene

Known as: B5, RHOTEKIN, RTKN 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism
Clone A colon carcinoma cells develop fanshaped lamellae and exhibit random migration when plated on laminin, processes that… 
2016
2016
Silencing of RTKN2 by siRNA suppresses proliferation, and induces G1 arrest and apoptosis in human bladder cancer cells.
Human bladder cancer is the most common urological malignancy in China. One of the causes of carcinogenesis in the cancer may be… 
2009
2009
Interaction of a multi-domain adaptor protein, vinexin, with a Rho-effector, Rhotekin
Among various effector proteins for the Rho small GTPase, the function(s) of Rhotekin is almost unknown. We have identified a… 
2009
2009
RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4+ Lymphocytes
The gene for Rhotekin 2 (RTKN2) was originally identified in a promyelocytic cell line resistant to oxysterol-induced apoptosis… 
2006
2006
Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons
2006
2006
Possible interaction of a Rho effector, Rhotekin, with a PDZ-protein, PIST, at synapses of hippocampal neurons
2004
2004
Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2.
2003
2003
The C Terminus of YopT Is Crucial for Activity and the N Terminus Is Crucial for Substrate Binding
ABSTRACT Recently, it was shown that Yersinia outer protein T (YopT) belongs to a new family of cysteine proteases containing… 
2002
2002
Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells.
It has been previously suggested that leukotriene-induced Ca2+ signalling is mediated through a Rho-dependent process, but… 
2000
2000
Molecular cloning, expression characterization, and mapping of a novel putative inhibitor of rho GTPase activity, RTKN, to D2S145-D2S286.
The Rho proteins are a class of small molecular GTPases that regulate multiple fundamental cellular processes by mediating the G… 
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