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RTKN gene

Known as: B5, RHOTEKIN, RTKN 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Let-7a inhibits tumor cell growth and metastasis by directly targeting RTKN in human colon cancer.
Highly Cited
2006
Highly Cited
2006
Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.
PURPOSE To assess the significance of Rho-kinase-dependent contractility in TGF-beta-induced myofibroblast transdifferentiation… 
2006
2006
Identification of a PDZ protein, PIST, as a binding partner for Rho effector Rhotekin: biochemical and cell-biological characterization of Rhotekin-PIST interaction.
Among various effector proteins for the small GTPase Rho, the function(s) of Rhotekin is (are) almost unknown. We have identified… 
Highly Cited
2005
Highly Cited
2005
Possible role of Rho/Rhotekin signaling in mammalian septin organization
There is growing evidence for crosstalk between septin filaments and actin cytoskeleton which is regulated by Rho family of… 
Highly Cited
2004
Highly Cited
2004
Interleukin-1β Induces a Reactive Astroglial Phenotype via Deactivation of the Rho GTPase–Rock Axis
The cytokine interleukin-1β (IL-1β) is critical to the formation of an astrocytic scar after CNS injury, but the mechanisms by… 
2004
2004
Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway.
AIM Intrahepatic extension is the main cause of liver failure and death in hepatocellular carcinoma patients. The small GTPase… 
Highly Cited
2003
Highly Cited
2003
Requirement of RhoA activity for increased nuclear factor kappaB activity and PC-3 human prostate cancer cell invasion.
To determine the molecular mechanisms of aggressive prostate cancer behavior, we studied RhoGTPases in high and low invasive… 
Highly Cited
2001
Highly Cited
2001
Rho activation in excitatory agonist-stimulated vascular smooth muscle.
Small GTPase Rho and its downstream effector, Rho kinase, have been implicated in agonist-stimulated Ca(2+) sensitization of 20… 
2001
2001
Thrombin-induced activation of RhoA in platelet shape change.
Thrombin-induced activation of RhoA and its involvement in the regulation of myosin II light chain(20) phosphorylation (MLC-P) in… 
Highly Cited
2000
Highly Cited
2000
Rhoa Function in Lamellae Formation and Migration Is Regulated by the α6β4 Integrin and Camp Metabolism
Clone A colon carcinoma cells develop fan-shaped lamellae and exhibit random migration when plated on laminin, processes that… 
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