R. Morishita

Publications106
h-index31
Citations2,728
Highly Influential Citations92
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Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin.
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Riluzole enhances expression of brain‐derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus
TLDR
Intraventricular administration of BDNF‐specific antibodies blocked such riluzole effects, suggesting that BDNF increase is necessary for the promotion of precursor proliferation, and suggests the basis for a new strategy for treatment of memory dysfunction.
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UV-Sensitive Photoreceptor Protein OPN5 in Humans and Mice
TLDR
This work reports that mouse neuropsin (OPN5) encoded by the Opn5 gene exhibited an absorption maximum at 380 nm when reconstituted with 11-cis-retinal, and suggests that OPN5 triggers a UV-sensitive Gi-mediated signaling pathway in the mammalian tissues.
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Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.
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GABAB receptors couple to G proteins Go, G∗ o and G·i1 but not to Gi2
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Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation
TLDR
The present results indicate possible functions of dysbindin-1 at the postsynapse in the regulation of dendritic spine morphogenesis through the interaction with WAVE2 and Abi-1.
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Sept8 controls the binding of vesicle‐associated membrane protein 2 to synaptophysin
TLDR
It is suggested that Sept8 may participate in the process of the SNARE complex formation and subsequent neurotransmitter release and the Sept8‐VAMP2 interaction is disrupted by synaptosome‐associated protein of 25 kDa.
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Identification of lung major GTP-binding protein as Gi2 and its distribution in various rat tissues determined by immunoassay.
TLDR
The concentrations of Gi2 alpha were constant in the rat brain throughout ontogenic development, in contrast with those of Go alpha which were markedly increased with age.
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Regulation of Rac and Cdc42 Pathways by Gi during Lysophosphatidic Acid-induced Cell Spreading*
TLDR
Findings indicate that both Gαi and Gβγ stimulate Rac and Cdc42 pathways with lysophosphatidic acid-induced cell spreading on fibronectin, suggesting a role for phosphorylation of the protein.
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Differential Interactions of the C terminus and the Cytoplasmic I-II Loop of Neuronal Ca2+ Channels with G-protein α and βγ Subunits
TLDR
Loop 1 of N- and P/Q-type Ca2+ channels is defined as an interaction site for Gβγ and the C termini for Gα and in vitro binding analysis for N-and-P/ Q-type channels revealed direct interaction of Gα with C-terminal fusion proteins as well as direct interaction with loop 1 fusion proteins.
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