RTA 408

Known as: Nrf2 Activator RTA 408 
A member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
024620072017

Papers overview

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2016
2016
Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is an important factor in the pathogenesis of age-related… (More)
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2015
2015
Semi-synthetic triterpenoids are antioxidant inflammation modulator (AIM) compounds that inhibit tumor cell growth and metastasis… (More)
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2015
2015
BACKGROUND Topical application of the synthetic triterpenoid RTA 408 to rodents elicits a potent dermal cytoprotective phenotype… (More)
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2015
2015
Bone marrow suppression due to exposure to ionizing radiation is a significant clinical problem associated with radiation therapy… (More)
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2015
2015
BACKGROUND AND PURPOSE Intracerebral hemorrhage (ICH) represents a devastating form of stroke for which there is no effective… (More)
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2014
2014
Free radicals produced during cancer radiotherapy often leads to dermatitis, with the insult ranging from mild erythema to moist… (More)
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2013
2013
RTA 408 is a member of the synthetic oleanane triterpenoid class of compounds known to potently activate the cytoprotective… (More)
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2013
2013
AIMS Mutant protein aggregation (PA) cardiomyopathy (MPAC) is characterized by reductive stress (RS), PA (of chaperones and… (More)
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Highly Cited
2007
Highly Cited
2007
The transcriptional factor Nrf2 has a unique role in various physiological stress conditions, but its contribution to ischemia… (More)
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Highly Cited
2007
Highly Cited
2007
The p53 tumor suppressor is a sequence-specific pleiotropic transcription factor that coordinates cellular responses to DNA… (More)
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