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RTA 408

Known as: Nrf2 Activator RTA 408 
A member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2… 
National Institutes of Health

Papers overview

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2020
2020
Label Free Quantitative Proteomic using Progenesis QI proteomics Reveals Novel Mechanism of Redox Regulation in Skeletal Muscles.
There is a high production of reactive oxygen species in skeletal muscle during stress such as exercise. The Nrf2/Keap1 pathway… 
2019
2019
Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates the Hepatoprotective Effects of Remote Ischemic Conditioning in Hemorrhagic Shock.
AIMS Remote ischemic conditioning (RIC) protects against organ ischemia/reperfusion injury in experimental and clinical settings… 
2019
2019
(Asea in DMD Conferinta Ramnicu Sarat 2.11.2019) Efectele Remarcabile Ale Suplimentului Redox "Asea"® în 2 Cazuri de Distrofie Musculară Duchenne la Copil și Potențialul Terapeutic al Asea în Bolile…
TITLE IN ENGLISH: The remarkable effects of " >® redox supplement" (ARS) in 2 cases of Duchenne muscular dystrophy in children… 
2017
2017
Hyperactivation of Nrf 2 in early tubular development induces nephrogenic diabetes insipidus
NF-E2-related factor-2 (Nrf2) regulates cellular responses to oxidative and electrophilic stress. Loss of Keap1 increases Nrf2… 
2015
2015
Animal Model of Autistic Regression: Link to Toxicant-Induced Oxidative Stress
Kanner, in his initial case study report defining autism, concluded .... “We must, then, assume that these children have come… 
2015
2015
The NO-cGMP pathway participates in vascular adaptation to oxidative stress in Nrf2 KO mice
Background Endothelial dysfunction is considered both as cause and consequence of oxidative stress. Mice lacking the… 
2014
2014
Radiation Protection of the Gastrointestinal Tract and Growth Inhibition of Prostate Cancer Xenografts by a Single Compound
Normal tissue toxicity markedly reduces the therapeutic index of genotoxic anticancer agents, including ionizing radiation… 
2013
2013
[Effects of NF-E2-related factor-2 promoter polymorphism on lipopolysaccharide-induced inflammatory responses in macrophages].
OBJECTIVE To explore the effects of NF-E2-related factor-2 (NRF2)-617C/A promoter polymorphism on NRF2 expression as well as… 
Review
2012
Review
2012
NRF2 molecule of the month
NRF2 – nuclear factor erythroid 2-related factor 2 is also known as GA binding protein transcription factor, alpha subunit 60kDa… 
2007
2007
[Prothyomosin alpha interaction with KEAP1 doesn't lead to prothymosin alpha ubiquination and degradation].
Prothymosin alpha (ProTalpha) is a highly conserved protein in vertebrates that possesses a number of biological functions. One… 
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