FAQ

RPS6KB1 gene

Known as: p70 S6 KINASE, ALPHA, S6K1, p70(S6K)-ALPHA 
This gene is involved in protein phosphorylation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
051019992017

Related topics

Related topics

7 relations
PhosphorylationRPS6KA4 geneRibosomal Protein S6 Kinase Beta-1Serine/Threonine Phosphorylation
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Narrower (1)

RPS6KB1 wt Allele

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
RPS6KB1 gene
Signal Transduction
Ribosomal Protein S6 Kinase Beta-1
Phosphorylation
Translational Regulation
RPS6KB1 wt Allele

Papers overview

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2015
2015
miR-195 Inhibits Tumor Progression by Targeting RPS6KB1 in Human Prostate Cancer.
PURPOSE To investigate the involvement of hsa-miRNA-195-5p (miR-195) in progression and prognosis of human prostate cancer… (More)
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2011
2011
Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer.
RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 are involved in several pathways central to the carcinogenic process, including… (More)
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2007
2007
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
The 70 kDa ribosomal protein S6 kinase (RPS6KB1), located at 17q23, is amplified and overexpressed in 10–30% of primary breast… (More)
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Highly Cited
2006
Highly Cited
2006
Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components.
Desmoplastic medulloblastoma (DMB) is a malignant cerebellar tumour composed of two distinct tissue components, pale islands and… (More)
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2006
2006
Insulin and oxidative stress modulate proliferation of rat ovarian theca-interstitial cells through diverse signal transduction pathways.
Insulin and moderate oxidative stress stimulate proliferation of ovarian theca-interstitial cells. The effects of these agents on… (More)
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2004
2004
ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers.
Breast cancer risk is greatly increased in women who carry mutations in the BRCA1 or BRCA2 genes. Because breast cancer… (More)
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2002
2002
Allelic gain and amplification on the long arm of chromosome 17 in anaplastic meningiomas.
Using comparative genomic hybridization (CGH) we have previously identified amplification at 17q21-qter as a common aberration in… (More)
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2001
2001
PS6K amplification characterizes a small subset of anaplastic meningiomas.
PS6K, a putative oncogene mapped to chromosome 17q23, encodes a serine/threonine kinase, which phosphorylates ribosomal subunit 6… (More)
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2000
2000
17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genes.
Amplification of the 17q23 region occurs frequently in breast tumors. To characterize the structure of 17q23 amplicons and to… (More)
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1999
1999
Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer.
The application of comparative genomic hybridization to the analysis of genetic abnormalities in breast carcinoma has… (More)
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