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RPS6KB1 wt Allele

Known as: p70-alpha, PS6K, p70(S6K)-alpha 
Human RPS6KB1 wild-type allele is located in the vicinity of 17q23.1 and is approximately 57 kb in length. This allele, which encodes ribosomal… 
National Institutes of Health

Related topics

Related topics

7 relations
17q23.1PhosphorylationRibosomal Protein S6 Kinase Beta-1Serine/Threonine Phosphorylation

Broader (1)

RPS6KB1 gene

Papers overview

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2014
2014
Characterization of the mTOR pathway in human normal adrenal and adrenocortical tumors.
The mTOR pathway has recently been suggested as a new potential target for therapy in adrenocortical carcinomas (ACCs). The aim… 
2013
2013
Metformin and rapamycin are master-keys for understanding the relationship between cell senescent, aging and cancer
During the last decade it was established that conservative growth hormone/ insulin-like growth factor-1 (IGF-1) and target of… 
2013
2013
Effects of advanced age on whole-body protein synthesis and skeletal muscle mechanistic target of rapamycin signaling in horses.
OBJECTIVE To determine the effects of advanced age on whole-body protein synthesis and activation of the mechanistic target of… 
Review
2011
Review
2011
Perspectives of Targeting mTORC1–S6K1 in Cardiovascular Aging
The global population aging is accelerating and age-associated diseases including cardiovascular diseases become more challenging… 
2009
2009
Rescuing 3T3-L1 adipocytes from insulin resistance induced by stimulation of Akt-mammalian target of rapamycin/p70 S6 kinase (S6K1) pathway and serine phosphorylation of insulin receptor substrate-1…
Phosphorylation of insulin receptor substrate-1 (IRS-1) on serine residues has been recognized as a mechanism responsible for a… 
Review
2008
Review
2008
Modification of core body temperature by amino acid administration.
The feeling of warmth after a meal is caused by the ingestion of nutrients and the sensation is known as nutrition-induced… 
2007
2007
A Fas-Associated Death Domain Protein/Caspase-8-Signaling Axis Promotes S-Phase Entry and Maintains S6 Kinase Activity in T Cells Responding to IL-21
Fas-associated death domain protein (FADD) constitutes an essential component of TNFR-induced apoptotic signaling. Paradoxically… 
2006
2006
S6k1 is not required for Pten-deficient neuronal hypertrophy
2005
2005
IGF-I activates the eIF4F system in cardiac muscle in vivo
IGF-I acutely stimulates protein synthesis in cardiac muscle through acceleration of mRNA translation. In the present study, we… 
2000
2000
Mitogen-independent phosphorylation of S6K1 and decreased ribosomal S6 phosphorylation in senescent human fibroblasts.
The p70 ribosomal S6 kinase (S6K1) is rapidly activated following growth factor stimulation of quiescent fibroblasts and… 
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