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Ribosomal Protein S6 Kinase Beta-1

Known as: Ribosomal Protein S6 Kinase I, p70-S6K, S6 Kinase-Related Kinase 
Ribosomal protein S6 kinase beta-1 (525 aa, ~59 kDa) is encoded by the human RPS6KB1 gene. This protein is involved in phosphorylation of ribosomal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The mTORC1 and mTORC2 pathways regulate cell growth, proliferation, and survival. We identify DEPTOR as an mTOR-interacting… Expand
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Highly Cited
2007
Highly Cited
2007
The heterotrimeric mTORC1 protein kinase nucleates a signaling network that promotes cell growth in response to insulin and… Expand
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Highly Cited
2007
Highly Cited
2007
The Target of Rapamycin (TOR) protein is a Ser/Thr kinase that functions in two distinct multiprotein complexes: TORC1 and TORC2… Expand
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Highly Cited
2007
Highly Cited
2007
Rapamycin and several analogs, such as CCI-779 and RAD001, are currently undergoing clinical evaluation as anticancer agents. In… Expand
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Highly Cited
2006
Highly Cited
2006
The mTOR kinase controls cell growth, proliferation, and survival through two distinct multiprotein complexes, mTORC1 and mTORC2… Expand
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Highly Cited
2005
Highly Cited
2005
The mammalian target of rapamycin (mTOR) pathway integrates insulin and nutrient signaling in numerous cell types. Recent studies… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT The mammalian target of rapamycin (mTOR) integrates nutrient and mitogen signals to regulate cell growth (increased cell… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Activation of 40S ribosomal protein S6 kinases (S6Ks) is mediated by anabolic signals triggered by hormones, growth… Expand
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Highly Cited
2002
Highly Cited
2002
The S/T-protein kinases activated by phosphoinositide 3-kinase (PI3K) regulate a myriad of cellular processes. Here, we show that… Expand
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Highly Cited
2002
Highly Cited
2002
The coordinated action of cell cycle progression and cell growth (an increase in cell size and cell mass) is critical for… Expand
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