Ribosomal Protein S6 Kinase Beta-1

Known as: Ribosomal Protein S6 Kinase I, p70-S6K, S6 Kinase-Related Kinase 
Ribosomal protein S6 kinase beta-1 (525 aa, ~59 kDa) is encoded by the human RPS6KB1 gene. This protein is involved in phosphorylation of ribosomal… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
The heterotrimeric mTORC1 protein kinase nucleates a signaling network that promotes cell growth in response to insulin and… (More)
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Highly Cited
2007
Highly Cited
2007
The Target of Rapamycin (TOR) protein is a Ser/Thr kinase that functions in two distinct multiprotein complexes: TORC1 and TORC2… (More)
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Highly Cited
2005
Highly Cited
2005
In response to nutrients, energy sufficiency, hormones, and mitogenic agents, S6K1 phosphorylates several targets linked to… (More)
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Highly Cited
2005
Highly Cited
2005
Mammalian cells respond to nutrient deprivation by inhibiting energy consuming processes, such as proliferation and protein… (More)
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Highly Cited
2004
Highly Cited
2004
Activation of 40S ribosomal protein S6 kinases (S6Ks) is mediated by anabolic signals triggered by hormones, growth factors, and… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The mammalian target of rapamycin (mTOR) and phosphatidylinositol 3-kinase (PI3K) signaling pathways promote cell… (More)
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Highly Cited
2004
Highly Cited
2004
The mammalian target of rapamycin (mTOR) integrates nutrient and mitogen signals to regulate cell growth (increased cell mass and… (More)
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Highly Cited
2002
Highly Cited
2002
The S/T-protein kinases activated by phosphoinositide 3-kinase (PI3K) regulate a myriad of cellular processes. Here, we show that… (More)
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Highly Cited
2000
Highly Cited
2000
The objectives of the present study were twofold: 1) to determine whether leucine is unique among the branched-chain amino acids… (More)
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