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RNA Ligase (ATP)

Known as: RNA Ligase (ATP) [Chemical/Ingredient], RNA ligase, Poly(ribonucleotide):poly(ribonucleotide)ligase (AMP-forming) 
An enzyme that catalyzes the conversion of linear RNA to a circular form by the transfer of the 5'-phosphate to the 3'-hydroxyl terminus. It also… Expand
National Institutes of Health

Related topics

Related topics

9 relations
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
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Narrower (2)

RtcB protein, Methanopyrus kandleritRNA Ligase

Papers overview

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Highly Cited
2006
Highly Cited
2006
RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward
T4 RNA ligase 2 (Rnl2) and kinetoplastid RNA editing ligases exemplify a family of RNA repair enzymes that seal 3'OH/5'PO(4… Expand
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Highly Cited
2004
Highly Cited
2004
Structure and mechanism of RNA ligase.
T4 RNA ligase 2 (Rnl2) exemplifies an RNA ligase family that includes the RNA editing ligases (RELs) of Trypanosoma and… Expand
2003
2003
Crystal structure of the 2'-5' RNA ligase from Thermus thermophilus HB8.
The 2'-5' RNA ligase family members are bacterial and archaeal RNA ligases that ligate 5' and 3' half-tRNA molecules with 2',3… Expand
Highly Cited
1996
Highly Cited
1996
The 2′-5′ RNA Ligase of Escherichia coli
An RNA ligase previously detected in extracts of Escherichia coli is capable of joining Saccharomyces cerevisiae tRNA splicing… Expand
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1995
1995
Trypanosoma brucei mitochondrial guide RNA-mRNA chimera-forming activity cofractionates with an editing-domain-specific endonuclease and RNA ligase and is mimicked by heterologous nuclease and RNA…
RNA editing in trypanosomes has been proposed to occur through transesterification or endonuclease cleavage and RNA ligation… Expand
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Highly Cited
1987
Highly Cited
1987
Bacteriophage T4 anticodon nuclease, polynucleotide kinase and RNA ligase reprocess the host lysine tRNA.
Host tRNAs cleaved near the anticodon occur specifically in T4‐infected Escherichia coli prr strains which restrict… Expand
Highly Cited
1983
Highly Cited
1983
Joining of RNA molecules with RNA ligase.
Publisher Summary T4 RNA ligase catalyzes the ATP-dependent phosphodiester bond formation between a 5´-terminal phosphate (donor… Expand
Highly Cited
1983
Highly Cited
1983
Anticodon loop size and sequence requirements for recognition of formylmethionine tRNA by methionyl-tRNA synthetase.
Previous work from our laboratory identified several specific sites in Escherichia coli tRNAfMet that are essential for… Expand
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1983
1983
Biotin and fluorescent labeling of RNA using T4 RNA ligase.
Biotin, fluorescein, and tetramethylrhodamine derivatives of P1-(6-aminohex-1-yl)-P2-(5'-adenosine) pyrophosphate were… Expand
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Highly Cited
1978
Highly Cited
1978
Enzymatic oligoribonucleotide synthesis with T4 RNA ligase.
The substrate specificity of T4 RNA ligase has been examined to determine whether the intermolecular reaction is sufficiently… Expand
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