RNA, Small Interfering

Known as: RNA, Short Interfering, Short Interfering RNA, Interfering RNA, Small 
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
RNA interference (RNAi) is a natural cellular mechanism that inhibits gene expression in a sequence-specific manner. In the last… (More)
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Highly Cited
2007
Highly Cited
2007
A major impediment in the treatment of neurological diseases is the presence of the blood–brain barrier, which precludes the… (More)
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Highly Cited
2005
Highly Cited
2005
Short interfering RNA (siRNA) is used in RNA interference technology to avoid non-target-related induction of type I interferon… (More)
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Highly Cited
2005
Highly Cited
2005
Arabidopsis thaliana contains four DICER-LIKE (DCL) genes with specialized functions in small RNA biogenesis for RNA interference… (More)
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Highly Cited
2004
Highly Cited
2004
Multicellular eukaryotes produce small RNA molecules (approximately 21-24 nucleotides) of two general types, microRNA (miRNA) and… (More)
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Highly Cited
2004
Highly Cited
2004
Small interfering RNA (siRNA) and microRNA silence genes at the transcriptional, posttranscriptional, and/or translational level… (More)
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Highly Cited
2003
Highly Cited
2003
Double-stranded RNAs approximately 21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to… (More)
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Highly Cited
2002
Highly Cited
2002
RNA silencing is a eukaryotic genome defence system that involves processing of double-stranded RNA (dsRNA) into 21-26 nt, short… (More)
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Highly Cited
2002
Highly Cited
2002
In many eukaryotes, expression of nuclear-encoded mRNA can be strongly inhibited by the presence of a double-stranded RNA (dsRNA… (More)
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Highly Cited
2001
Highly Cited
2001
We examined the role of ATP in the RNA interference (RNAi) pathway. Our data reveal two ATP-dependent steps and suggest that the… (More)
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