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RNA, Small Interfering
Known as:
RNA, Short Interfering
, Short Interfering RNA
, Interfering RNA, Small
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Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi…
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National Institutes of Health
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Related topics
Related topics
24 relations
Broader (2)
Antisense Elements (Genetics)
RNA
Narrower (10)
Atu027
CALAA-01
PF-04523655
Piwi-Interacting RNA
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Clinical Data Interchange Standards Consortium Terminology
In Blood
MicroRNAs
Process of secretion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Is there a future for cell-penetrating peptides in oligonucleotide delivery?
Soo Hyeon Lee
,
Bastien Castagner
,
J. Leroux
European journal of pharmaceutics and…
2013
Corpus ID: 6701335
Highly Cited
2012
Highly Cited
2012
Biodegradable copolymers with identical cationic segments and their performance in siRNA delivery.
Ruogu Qi
,
Shi Liu
,
+4 authors
X. Jing
Journal of Controlled Release
2012
Corpus ID: 27284296
Highly Cited
2010
Highly Cited
2010
In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers
P. Ofek
,
W. Fischer
,
M. Calderón
,
R. Haag
,
R. Satchi‐Fainaro
The FASEB Journal
2010
Corpus ID: 205366031
New targets for RNA interference (RNAi)‐based cancer therapy are constantly emerging from the increasing knowledge on key…
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Highly Cited
2010
Highly Cited
2010
Liposome-siRNA-Peptide Complexes Cross the Blood-Brain Barrier and Significantly Decrease PrPC on Neuronal Cells and PrPRES in Infected Cell Cultures
B. Pulford
,
Natalia Reim
,
+14 authors
M. Zabel
PLoS ONE
2010
Corpus ID: 10899600
Background Recent advances toward an effective therapy for prion diseases employ RNA interference to suppress PrPC expression and…
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Highly Cited
2009
Highly Cited
2009
Acid-responsive linear polyethylenimine for efficient, specific, and biocompatible siRNA delivery.
Min Suk Shim
,
Y. J. Kwon
Bioconjugate chemistry
2009
Corpus ID: 30121108
Efficient intracellular processes including cytosolic release and unpackaging of siRNA from the carrier in the cytoplasm are…
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Highly Cited
2009
Highly Cited
2009
Facile synthesis of multivalent folate-block copolymer conjugates via aqueous RAFT polymerization: targeted delivery of siRNA and subsequent gene suppression.
Adam W. York
,
Yilin Zhang
,
A. C. Holley
,
Yanlin Guo
,
Faqing Huang
,
C. McCormick
Biomacromolecules
2009
Corpus ID: 9455063
Cell specific delivery of small interfering ribonucleic acid (siRNA) using well-defined multivalent folate-conjugated block…
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Highly Cited
2008
Highly Cited
2008
Controlled delivery of plasmid DNA and siRNA to intracellular targets using ketalized polyethylenimine.
Min Suk Shim
,
Y. J. Kwon
Biomacromolecules
2008
Corpus ID: 21514349
A new polyethylenimine (PEI)-derived biodegradable polymer was synthesized as a nonviral gene carrier. Branches of PEI were…
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Highly Cited
2008
Highly Cited
2008
Chitosan-Thiamine Pyrophosphate as a Novel Carrier for siRNA Delivery
T. Rojanarata
,
P. Opanasopit
,
S. Techaarpornkul
,
T. Ngawhirunpat
,
U. Ruktanonchai
Pharmaceutical Research
2008
Corpus ID: 28814160
PurposeA novel siRNA carrier was formulated between chitosan (CS) and thiamine pyrophosphate (TPP). Their ability to deliver…
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Highly Cited
2005
Highly Cited
2005
Modification of professional antigen-presenting cells with small interfering RNA in vivo to enhance cancer vaccine potency.
Tae Woo Kim
,
Jin-Hyup Lee
,
+4 authors
T. Wu
Cancer Research
2005
Corpus ID: 17670867
RNA interference using small interfering RNA (siRNA) is an effective means of silencing gene expression in cells. Intradermal…
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Highly Cited
2002
Highly Cited
2002
p53 induces the expression of its antagonist p73ΔN, establishing an autoregulatory feedback loop
N. Kartasheva
,
A. Contente
,
C. Lenz-Stöppler
,
J. Roth
,
M. Dobbelstein
Oncogene
2002
Corpus ID: 5610283
The p53 tumor suppressor protein activates transcription and induces cell death. A close homologue of p53, termed p73, is…
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