CALAA-01

Significance CALAA-01 is a targeted nanoparticle containing siRNA that is a first-in-class experimental therapeutic for cancer… Expand

siRNA clinical trials: state of the art With the emergence of siRNA-based nanomedicine as a powerful therapeutic strategy for… Expand

The approval of drugs for human use by the US Food and Drug Administration (FDA) through the Center for Drug Evaluation and… Expand

S ince the discovery of RNA interference (RNAi) in 1998, researchers have hoped to use the gene-silencing technique to shut down… Expand

Experimental therapeutics developed to exploit RNA interference (RNAi) are now in clinical studies. Here, the translation from… Expand