CALAA-01
National Institutes of Health
Papers overview
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Significance CALAA-01 is a targeted nanoparticle containing siRNA that is a first-in-class experimental therapeutic for cancer…
siRNA clinical trials: state of the art With the emergence of siRNA-based nanomedicine as a powerful therapeutic strategy for…
The approval of drugs for human use by the US Food and Drug Administration (FDA) through the Center for Drug Evaluation and…
S ince the discovery of RNA interference (RNAi) in 1998, researchers have hoped to use the gene-silencing technique to shut down…
Experimental therapeutics developed to exploit RNA interference (RNAi) are now in clinical studies. Here, the translation from…