RNA, Messenger, Splicing

Known as: mRNA splicing 
OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0204019842018

Related topics

Related topics

4 relations
Group I intron splicingGroup II intron splicingSpliceosomes

Broader (1)

RNA Splicing

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
RNA, Messenger, Splicing
RNA Splicing
Spliceosomes
Group I intron splicing
Group II intron splicing

Papers overview

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Highly Cited
2014
Highly Cited
2014
circRNA biogenesis competes with pre-mRNA splicing.
Circular RNAs (circRNAs) are widely expressed noncoding RNAs. However, their biogenesis and possible functions are poorly… (More)
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Highly Cited
2014
Highly Cited
2014
FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
The role of Fat Mass and Obesity-associated protein (FTO) and its substrate N6-methyladenosine (m6A) in mRNA processing and… (More)
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Highly Cited
2012
Highly Cited
2012
Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
The muscleblind-like (Mbnl) family of RNA-binding proteins plays important roles in muscle and eye development and in myotonic… (More)
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Highly Cited
2008
Highly Cited
2008
SKAR Links Pre-mRNA Splicing to mTOR/S6K1-Mediated Enhanced Translation Efficiency of Spliced mRNAs
Different protein complexes form on newly spliced mRNA to ensure the accuracy and efficiency of eukaryotic gene expression. For… (More)
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Highly Cited
2007
Highly Cited
2007
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing.
Both microRNAs and alternative pre-mRNA splicing have been implicated in the development of the nervous system (NS), but… (More)
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Highly Cited
2007
Highly Cited
2007
Transcript Specificity in Yeast Pre-mRNA Splicing Revealed by Mutations in Core Spliceosomal Components
Appropriate expression of most eukaryotic genes requires the removal of introns from their pre-messenger RNAs (pre-mRNAs), a… (More)
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Highly Cited
2005
Highly Cited
2005
Escaping the Nuclear Confines: Signal-Dependent Pre-mRNA Splicing in Anucleate Platelets
Platelets are specialized hemostatic cells that circulate in the blood as anucleate cytoplasts. We report that platelets… (More)
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Highly Cited
2000
Highly Cited
2000
Mutations affecting mRNA splicing are the most common molecular defects in patients with neurofibromatosis type 1.
Neurofibromatosis type 1 (NF1) is one of the most common inherited disorders in humans and is caused by mutations in the NF1 gene… (More)
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Highly Cited
1998
Highly Cited
1998
A Novel Function for SMN, the Spinal Muscular Atrophy Disease Gene Product, in Pre-mRNA Splicing
Spinal muscular atrophy (SMA) is a common motor neuron degenerative disease that results from reduced levels of, or mutations in… (More)
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Highly Cited
1994
Highly Cited
1994
Localization of pre-mRNA splicing in mammalian nuclei
IN mammalian nuclei, precursor messenger RNA splicing factors are distributed non-uniformly. Antibodies directed against struc… (More)
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