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Group I intron splicing

The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of… 
National Institutes of Health

Papers overview

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2010
2010
1 Chapter I: Introduction 3 General Importance of RNA in Biology 4 Group I Introns 8 Protein-facilitated Group I Intron Splicing… 
Highly Cited
2005
Highly Cited
2005
We report the 3.4 angstrom crystal structure of a catalytically active group I intron splicing intermediate containing the… 
Highly Cited
2004
Highly Cited
2004
A recently reported crystal structure of an intact bacterial group I self-splicing intron in complex with both its exons provided… 
Highly Cited
2003
Highly Cited
2003
We determined the crystal structure of a bifunctional group I intron splicing factor and homing endonuclease, termed the I-AniI… 
2002
2002
Previously it was shown that the Aspergillus nidulans (A.n.) mitochondrial COB intron maturase, I-AniI, facilitates splicing of… 
Highly Cited
2002
Highly Cited
2002
RNA is becoming an important therapeutic target. Many potential RNA targets require secondary or tertiary structure for function… 
Highly Cited
2000
Highly Cited
2000
ABSTRACT We previously demonstrated that pentamidine, which has been clinically used against Pneumocystis carinii, inhibits in… 
Highly Cited
1995
Highly Cited
1995
The observation that the large ribosomal RNA intron of Tetrahymena is spliced 20-50-fold more rapidly in vivo than in vitro…