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RN 1734

Known as: RN-1734, RN1734 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
051020092017

Related topics

Related topics

1 relation

Broader (1)

Sulfonamides

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
RN 1734
Sulfonamides

Papers overview

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2015
2015
Sex differences in the role of transient receptor potential (TRP) channels in endothelium-dependent vasorelaxation in porcine isolated coronary arteries.
Endothelial and smooth muscle Transient Receptor Potential (TRP) channels contribute to regulation of vascular tone. We have… (More)
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2015
2015
The depressor response to intracerebroventricular hypotonic saline is sensitive to TRPV4 antagonist RN1734
Several reports have shown that the periventricular region of the brain, including the paraventricular nucleus (PVN), is critical… (More)
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2015
2015
Co-administration of transient receptor potential vanilloid 4 (TRPV4) and TRPV1 antagonists potentiate the effect of each drug in a rat model of cystitis.
OBJECTIVE To investigate transient receptor potential vanilloid 4 (TRPV4) expression in bladder afferents and study the effect of… (More)
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2015
2015
Uniaxial cyclic stretch stimulates TRPV4 to induce realignment of human embryonic stem cell-derived cardiomyocytes.
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) in culture are randomly organized and do not typically show… (More)
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2013
2013
TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension.
Transient receptor potential vanilloid 4 (TRPV4) is a mechanosensitive channel in pulmonary arterial smooth muscle cells (PASMCs… (More)
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2012
2012
The Increased Activity of TRPV4 Channel in the Astrocytes of the Adult Rat Hippocampus after Cerebral Hypoxia/Ischemia
The polymodal transient receptor potential vanilloid 4 (TRPV4) channel, a member of the TRP channel family, is a calcium… (More)
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2012
2012
Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone.
Endothelial cell (EC) Ca(2+)-activated K channels (SK(Ca) and IK(Ca) channels) generate hyperpolarization that passes to the… (More)
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2012
2012
Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat.
AIMS Transient receptor potential vanilloid 4 (TRPV4) may affect afferent pathways innervating the bladder. We investigated the… (More)
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2011
2011
Activation of TRPV4 on dural afferents produces headache-related behavior in a preclinical rat model.
BACKGROUND The mechanisms contributing to the pain of migraine are poorly understood although activation of afferent nociceptors… (More)
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2009
2009
Identification and characterization of novel TRPV4 modulators.
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands… (More)
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