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RN 1734

Known as: RN-1734, RN1734 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Sulfonamides

Papers overview

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2018
2018
Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins.
Cold-inducible RNA-binding protein (CIRP), RNA-binding motif protein 3 (RBM3) and serine and arginine rich splicing factor 5… Expand
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2017
2017
Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced nitric oxide production and vasorelaxation in rabbit mesenteric arteries
Stimulation of calcium-sensing receptors (CaSR) by increasing the external calcium concentration (Ca2 +]o) induces endothelium… Expand
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2015
2015
Co-administration of transient receptor potential vanilloid 4 (TRPV4) and TRPV1 antagonists potentiate the effect of each drug in a rat model of cystitis.
OBJECTIVE To investigate transient receptor potential vanilloid 4 (TRPV4) expression in bladder afferents and study the effect of… Expand
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2013
2013
Arachidonic Acid–Induced Dilation in Human Coronary Arterioles: Convergence of Signaling Mechanisms on Endothelial TRPV4‐Mediated Ca2+ Entry
Background Arachidonic acid (AA) and/or its enzymatic metabolites are important lipid mediators contributing to endothelium… Expand
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2013
2013
TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension.
Transient receptor potential vanilloid 4 (TRPV4) is a mechanosensitive channel in pulmonary arterial smooth muscle cells (PASMCs… Expand
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Highly Cited
2012
Highly Cited
2012
Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone
Endothelial cell (EC) Ca2+-activated K channels (SKCa and IKCa channels) generate hyperpolarization that passes to the adjacent… Expand
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2012
2012
Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat.
AIMS Transient receptor potential vanilloid 4 (TRPV4) may affect afferent pathways innervating the bladder. We investigated the… Expand
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Highly Cited
2012
Highly Cited
2012
The Increased Activity of TRPV4 Channel in the Astrocytes of the Adult Rat Hippocampus after Cerebral Hypoxia/Ischemia
The polymodal transient receptor potential vanilloid 4 (TRPV4) channel, a member of the TRP channel family, is a calcium… Expand
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2011
2011
Activation of TRPV4 on dural afferents produces headache-related behavior in a preclinical rat model
Background: The mechanisms contributing to the pain of migraine are poorly understood although activation of afferent nociceptors… Expand
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Highly Cited
2009
Highly Cited
2009
Identification and characterization of novel TRPV4 modulators.
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands… Expand
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