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RIFAMYCIN SODIUM

Known as: 2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2h)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-Acetate, Sodium Salt, Rifamycin SV Sodium 
A sodium salt of rifamycin, an antibiotic produced by Streptomyces mediterranei which is used to treat mycobacterium infections.
National Institutes of Health

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Rifamycins

Papers overview

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2020
2020
A Semisynthetic Kanglemycin Shows In Vivo Efficacy against High-Burden Rifampicin Resistant Pathogens
Semisynthetic rifamycin derivatives such as rifampicin (Rif) are first line treatments for tuberculosis and other bacterial… 
Review
2012
Review
2012
In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
To assess the feasibility of using sandwich-cultured human hepatocytes (SCHHs) as a model to characterize transport kinetics for… 
2004
2004
Optimization of industrial production of rifamycin B by Amycolatopsis mediterranei . I. The role of colony morphology and nitrogen sources in productivity
A systematic approach to process optimization for production of rifamycin B was applied to a strain of Amycolatopsis mediterranei… 
Highly Cited
2001
Highly Cited
2001
Mutational Analysis and Reconstituted Expression of the Biosynthetic Genes Involved in the Formation of 3-Amino-5-hydroxybenzoic Acid, the Starter Unit of Rifamycin Biosynthesis in Amycolatopsis…
To investigate a novel branch of the shikimate biosynthesis pathway operating in the formation of 3-amino-5-hydroxybenzoic acid… 
Highly Cited
1992
Highly Cited
1992
New methods and strategies for the stereocontrolled synthesis of polypropionate-derived natural products
Abstract 
Highly Cited
1987
Highly Cited
1987
Oxygen radical damage to DNA by rifamycin SV and copper ions.
1981
1981
New rifamycins produced by a recombinant strain of Nocardia mediterranei.
A recombinant strain of Nocardia mediterranei was found to produce a number of new rifamycins which are structurally related to… 
1974
1974
Rifamycin biosynthesis: further studies on origin of the ansa chain and chromophore.
The metabolic origin of the ansa chain and chromophore of rifamycin S has been investigated by studying the incorporation of… 
1971
1971
Similar Effect of Rifampin and Other Rifamycin Derivatives on Vaccinia Virus Morphogenesis
Membrane-limited structures, resembling virus envelope precursors previously shown to form during the interruption of poxvirus… 
Highly Cited
1965
Highly Cited
1965
The effect of an intravenous infusion of rifamycin SV on the excretion of bilirubin, bromsulphalein, and indocyanine green in man.
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