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RHOG gene

Known as: RhoG, RAS HOMOLOG GENE FAMILY, MEMBER G, MGC125835 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
Summary Cell migration is commonly accompanied by protrusion of membrane ruffles and lamellipodia. In two-dimensional migration… 
Highly Cited
2007
Highly Cited
2007
Shigella IpgB1 promotes bacterial entry through the ELMO–Dock180 machinery
Shigella use a special mechanism to invade epithelial cells called 'the trigger mechanism of entry', which allows epithelial… 
Highly Cited
2006
Highly Cited
2006
Opposite Effects of Rho Family GTPases on Engulfment of Apoptotic Cells by Macrophages*
The efficient engulfment of apoptotic cells by professional or nonprofessional phagocytes is critical to maintain mammalian… 
Highly Cited
2006
Highly Cited
2006
Activation of Rac1 by RhoG regulates cell migration
Cell migration is essential for normal development and many pathological processes. Rho-family small GTPases play important roles… 
Highly Cited
2006
Highly Cited
2006
Dock4 is regulated by RhoG and promotes Rac-dependent cell migration.
Highly Cited
2003
Highly Cited
2003
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
The small GTPase Rac has a central role in regulating the actin cytoskeleton during cell migration and axon guidance. Elmo has… 
Highly Cited
2002
Highly Cited
2002
The Human Rho-GEF Trio and Its Target GTPase RhoG Are Involved in the NGF Pathway, Leading to Neurite Outgrowth
Highly Cited
2000
Highly Cited
2000
Small GTPase RhoG Is a Key Regulator for Neurite Outgrowth in PC12 Cells
ABSTRACT The Rho family of small GTPases has been implicated in cytoskeletal reorganization and subsequent morphological changes… 
Highly Cited
1997
Highly Cited
1997
The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells
Highly Cited
1992
Highly Cited
1992
Growth-regulated expression of rhoG, a new member of the ras homolog gene family
Cellular transition from the resting state to DNA synthesis involves master switches genes encoding transcriptional factors (e.g… 
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